Research output per year
Research output per year
- 1 - 50 out of 1,070 results
Search results
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2024
Angiotensin II Type 2 Receptor Agonism Alleviates Progressive Post-stroke Cognitive Impairment in Aged Spontaneously Hypertensive Rats
Alshammari, A., Pillai, B., Kamat, P., Jones, T. W., Bosomtwi, A., Khan, M. B., Hess, D. C., Li, W., Somanath, P. R., Ergul, A. & Fagan, S. C., 2024, (Accepted/In press) In: Translational Stroke Research.Research output: Contribution to journal › Article › peer-review
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A novel exosome based therapeutic intervention against neuroendocrine prostate cancer
Saini, S., Sreekumar, A., Nathani, S., Asante, D. M. & Simmons, M. N., Dec 2024, In: Scientific reports. 14, 1Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Colonic ketogenesis, a microbiota-regulated process, contributes to blood ketones and protects against colitis in mice
Bass, K., Sivaprakasam, S., Dharmalingam-Nandagopal, G., Thangaraju, M. & Ganapathy, V., Feb 21 2024, In: The Biochemical journal. 481, 4, p. 295-312 18 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Inactivation of adenosine receptor 2A suppresses endothelial-to-mesenchymal transition and inhibits subretinal fibrosis in mice
Yang, Q., Cai, Y., Ma, Q., Xiong, A., Xu, P., Zhang, Z., Xu, J., Zhou, Y., Liu, Z., Zhao, D., Asara, J., Li, W., Shi, H., Caldwell, R. B., Sodhi, A. & Huo, Y., 2024, In: Science Translational Medicine. 16, 737, eadk3868.Research output: Contribution to journal › Article › peer-review
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Indoximod-based chemo-immunotherapy for pediatric brain tumors: A first-in-children phase I trial
Johnson, T. S., MacDonald, T. J., Pacholczyk, R., Aguilera, D., Al-Basheer, A., Bajaj, M., Bandopadhayay, P., Berrong, Z., Bouffet, E., Castellino, R. C., Dorris, K., Eaton, B. R., Esiashvili, N., Fangusaro, J. R., Foreman, N., Fridlyand, D., Giller, C., Heger, I. M., Huang, C., Kadom, N., & 18 others, Feb 1 2024, In: Neuro-Oncology. 26, 2, p. 348-361 14 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
miR-410 Is a Key Regulator of Epithelial-to-Mesenchymal Transition with Biphasic Role in Prostate Cancer
Asante, D. M., Sreekumar, A., Nathani, S., Lee, T. J., Sharma, A., Patel, N., Simmons, M. N. & Saini, S., Jan 2024, In: Cancers. 16, 1, 48.Research output: Contribution to journal › Article › peer-review
Open Access -
SAMHD1 expression contributes to doxorubicin resistance and predicts survival outcomes in diffuse large B-cell lymphoma patients
Daddacha, W., Monroe, D., Schlafstein, A. J., Withers, A. E., Thompson, E. B., Danelia, D., Luong, N. C., Sesay, F., Rath, S. K., Usoro, E. R., Essien, M. E., Jung, A. T., Jiang, J. G., Hu, J., Mahboubi, B., Williams, A., Steinbeck, J. E., Yang, X., Buchwald, Z. S., Dynan, W. S., & 5 others, Mar 1 2024, In: NAR Cancer. 6, 1, zcae007.Research output: Contribution to journal › Article › peer-review
Open Access -
Simple virus-free mouse models of COVID-19 pathologies and oral therapeutic intervention
Zhu, H., Sharma, A. K., Aguilar, K., Boghani, F., Sarcan, S., George, M., Ramesh, J., Van Der Eerden, J., Panda, C. S., Lopez, A., Zhi, W., Bollag, R., Patel, N., Klein, K., White, J., Thangaraju, M., Lokeshwar, B. L., Singh, N. & Lokeshwar, V. B., Mar 15 2024, In: iScience. 27, 3, 109191.Research output: Contribution to journal › Article › peer-review
Open Access -
Simvastatin-Mediated Nrf2 Activation Induces Fetal Hemoglobin and Antioxidant Enzyme Expression to Ameliorate the Phenotype of Sickle Cell Disease
Xi, C., Palani, C., Takezaki, M., Shi, H., Horuzsko, A., Pace, B. S. & Zhu, X., Mar 2024, In: Antioxidants. 13, 3, 337.Research output: Contribution to journal › Article › peer-review
Open Access -
Stress biology: Complexity and multifariousness in health and disease
Mayer, M. P., Blair, L., Blatch, G. L., Borges, T. J., Chadli, A., Chiosis, G., de Thonel, A., Dinkova-Kostova, A., Ecroyd, H., Edkins, A. L., Eguchi, T., Fleshner, M., Foley, K. P., Fragkostefanakis, S., Gestwicki, J., Goloubinoff, P., Heritz, J. A., Heske, C. M., Hibshman, J. D., Joutsen, J., & 18 others, Feb 2024, In: Cell Stress and Chaperones. 29, 1, p. 143-157 15 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2023
Altered endocannabinoid metabolism compromises the brain-CSF barrier and exacerbates chronic deficits after traumatic brain injury in mice
Ahluwalia, M., Mcmichael, H., Kumar, M., Espinosa, M. P., Bosomtwi, A., Lu, Y., Khodadadi, H., Jarrahi, A., Khan, M. B., Hess, D. C., Rahimi, S. Y., Vender, J. R., Vale, F. L., Braun, M., Baban, B., Dhandapani, K. M. & Vaibhav, K., Mar 2023, In: Experimental Neurology. 361, 114320.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
A Non-Systemic Phosphodiesterase-5 Inhibitor Suppresses Colon Proliferation in Mice
Lee, A., Lebedyeva, I. O., Zhi, W., Senthil, V., Cheema, H., Brands, M. W., Bush, W., Lambert, N. A., Snipes, M. & Browning, D. D., Jun 2023, In: International journal of molecular sciences. 24, 11, 9397.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
A novel SYNJ1 homozygous variant causing developmental and epileptic encephalopathy in an Afro-Caribbean individual
Maj, M., Taylor, C. L., Landau, K., Toriello, H. V., Li, D., Bhoj, E. J., Hakonarson, H., Nelson, B., Gluschitz, S., Walker, R. H. & Sobering, A. K., Jan 2023, In: Molecular Genetics and Genomic Medicine. 11, 1, e2064.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Belief in Research, Religious Coping, and Willingness to Participate in Clinical Trials Among African American Patients With Hematologic Malignancies: A Pilot Study
Petty, M., Chernecky, C., Shishkina, I., Maihle, N., Pawl, J., Waller, J., Young, L. & Zadinsky, J., Feb 1 2023, In: Journal of Clinical Pathways. 9, 1Research output: Contribution to journal › Article › peer-review
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Capsaicin binds the N-terminus of Hsp90, induces lysosomal degradation of Hsp70, and enhances the anti-tumor effects of 17-AAG (Tanespimycin)
Patwardhan, C. A., Kommalapati, V. K., Llbiyi, T., Singh, D., Alfa, E., Horuzsko, A., Korkaya, H., Panda, S., Reilly, C. A., Popik, V. & Chadli, A., Dec 2023, In: Scientific reports. 13, 1, 13790.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Curating a Case Catalog: Development and Implementation of a Process for Revising Small Group Teaching Cases for Pre-clerkship Medical Education
Bruner, L. P., Szymik, B., House, E., Chappell, M. T., Teshager, D. & Baldwin, A., Feb 2023, In: Medical Science Educator. 33, 1, p. 215-222 8 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Development of a Transparent Transgenic Zebrafish Cellular Phenotype Tg(6xNF-kB:EGFP); Casper(roy−/−, nacre−/−) to Study NF-kB Activity
Rajpurohit, S. K., Ouellette, L., Sura, S., Appiah, C., O’Keefe, A., McCarthy, K., Kandepu, U., Ye Mon, M., Kimmerling, K., Arora, V. & Lokeshwar, B. L., Jul 2023, In: Biomedicines. 11, 7, 1985.Research output: Contribution to journal › Article › peer-review
Open Access -
DNA-PK is activated by SIRT2 deacetylation to promote DNA double-strand break repair by non-homologous end joining
Head, P. S. E., Kapoor-Vazirani, P., Nagaraju, G. P., Zhang, H., Rath, S. K., Luong, N. C., Haji-Seyed-Javadi, R., Sesay, F., Wang, S. Y., Duong, D. M., Daddacha, W., Minten, E. V., Song, B., Danelia, D., Liu, X., Li, S., Ortlund, E. A., Seyfried, N. T., Smalley, D. M., Wang, Y., & 5 others, Aug 25 2023, In: Nucleic Acids Research. 51, 15, p. 7972-7987 16 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Enniatin A Analogues as Novel Hsp90 Inhibitors that Modulate Triple-Negative Breast Cancer
Serwetnyk, M. A., Crowley, V. M., Brackett, C. M., Carter, T. R., Elahi, A., Kommalapati, V. K., Chadli, A. & Blagg, B. S. J., Dec 14 2023, In: ACS Medicinal Chemistry Letters. 14, 12, p. 1785-1790 6 p.Research output: Contribution to journal › Article › peer-review
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Enniatin A inhibits the chaperone Hsp90 and unleashes the immune system against triple-negative breast cancer
Eisa, N. H., Crowley, V. M., Elahi, A., Kommalapati, V. K., Serwetnyk, M. A., Llbiyi, T., Lu, S., Kainth, K., Jilani, Y., Marasco, D., El Andaloussi, A., Lee, S., Tsai, F. T. F., Rodriguez, P. C., Munn, D., Celis, E., Korkaya, H., Debbab, A., Blagg, B. & Chadli, A., Dec 15 2023, In: iScience. 26, 12, 108308.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Epigenetic Regulation of Hepatic Lipid Metabolism by DNA Methylation
Wang, S., Zha, L., Cui, X., Yeh, Y. T., Liu, R., Jing, J., Shi, H., Chen, W., Hanover, J., Yin, J., Yu, L., Xue, B. & Shi, H., Jul 18 2023, In: Advanced Science. 10, 20, 2206068.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Exploring Academic Performance of Medical Students in an Integrated Hybrid Curriculum by Gender
Hesse, D. L. W., Ramsey, L. M., Bruner, L. P., Vega-Castillo, C. S., Teshager, D., Hill, J. R., Bond, M. T., Sperr, E. V., Baldwin, A. & Medlock, A. E., Apr 2023, In: Medical Science Educator. 33, 2, p. 353-357 5 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Identification of genetic risk loci and causal insights associated with Parkinson's disease in African and African admixed populations: a genome-wide association study
Nigeria Parkinson Disease Research Network, International Parkinson's Disease Genomics Consortium Africa, Black and African American Connections to Parkinson's Disease Study Group, 23andMe Research Team & Global Parkinson's Genetics Program, Nov 2023, In: The Lancet Neurology. 22, 11, p. 1015-1025 11 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
IRF8 Regulates Intrinsic Ferroptosis through Repressing p53 Expression to Maintain Tumor Cell Sensitivity to Cytotoxic T Lymphocytes
Poschel, D. B., Kehinde-Ige, M., Klement, J. D., Yang, D., Merting, A. D., Savage, N. M., Shi, H. & Liu, K., Jan 2023, In: Cells. 12, 2, 310.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Myeloid PFKFB3-mediated glycolysis promotes kidney fibrosis
Yang, Q., Huo, E., Cai, Y., Zhang, Z., Dong, C., Asara, J. M., Shi, H. & Wei, Q., 2023, In: Frontiers in immunology. 14, 1259434.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
NET formation is a default epigenetic program controlled by PAD4 in apoptotic neutrophils
Zhu, Y. P., Speir, M., Tan, Z. H., Lee, J. C., Nowell, C. J., Chen, A. A., Amatullah, H., Salinger, A. J., Huang, C. J., Wu, G., Peng, W., Askari, K., Griffis, E., Ghassemian, M., Santini, J., Gerlic, M., Kiosses, W. B., Catz, S. D., Hoffman, H. M., Greco, K. F., & 6 others, Dec 2023, In: Science Advances. 9, 51, eadj1397.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
New NSAID Conjugates as Potent and Selective COX-2 Inhibitors: Synthesis, Molecular Modeling and Biological Investigation
Bokhtia, R. M., Panda, S. S., Girgis, A. S., Samir, N., Said, M. F., Abdelnaser, A., Nasr, S., Bekheit, M. S., Dawood, A. S., Sharma, H., Wade, M., Sharma, S. K. & Ghanim, A. M., Feb 2023, In: Molecules. 28, 4, 1945.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Nonclassical monocytes potentiate anti-tumoral CD8+ T cell responses in the lungs
Padgett, L. E., Marcovecchio, P. M., Olingy, C. E., Araujo, D. J., Steel, K., Dinh, H. Q., Alimadadi, A., Zhu, Y. P., Meyer, M. A., Kiosses, W. B., Thomas, G. D. & Hedrick, C. C., 2023, In: Frontiers in immunology. 14, 1101497.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Nrf2 sensitizes ferroptosis through L-2-hydroxyglutarate–mediated chromatin modifications in sickle cell disease
Xi, C., Pang, J., Zhi, W., Chang, C. S. S., Siddaramappa, U., Shi, H., Horuzsko, A., Pace, B. S. & Zhu, X., Jul 27 2023, In: Blood. 142, 4, p. 382-396 15 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Peer-Assisted Learning in Undergraduate Medical Education for Resilience and Well-being
Snapp, C., Bassett, C., Baldwin, A., Hill, J. R. & DeBusk, R., Feb 2023, In: Medical Science Educator. 33, 1, p. 5-6 2 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Radiolabeled Biodistribution of Expansile Nanoparticles: Intraperitoneal Administration Results in Tumor Specific Accumulation
Colby, A. H., Kirsch, J., Patwa, A. N., Liu, R., Hollister, B., McCulloch, W., Burdette, J. E., Pearce, C. J., Oberliels, N. H., Colson, Y. L., Liu, K. & Grinstaff, M. W., Feb 14 2023, In: ACS Nano. 17, 3, p. 2212-2221 10 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Targeting TREM1 augments antitumor T cell immunity by inhibiting myeloid-derived suppressor cells and restraining anti–PD-1 resistance
Ajith, A., Mamouni, K., Horuzsko, D. D., Musa, A., Dzutsev, A. K., Fang, J. R., Chadli, A., Zhu, X., Lebedyeva, I. O., Trinchieri, G. & Horuzsko, A., Nov 1 2023, In: Journal of Clinical Investigation. 133, 21, e167951.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
T-Cell Clonality, Functional Changes, and Clinical Response after Dupilumab in Atopic Dermatitis and Asthma Patients
Dilley, M., Loop, L., Croker, B., Aceves, S., Lewis, N., Zhu, Y., Lee, J., Shamie, I., Chiang, A., Tambay, A. & Geng, B., Feb 2023, In: Journal of Allergy and Clinical Immunology.Research output: Contribution to journal › Article › peer-review
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Teaching perspectives on the communication of difficult news of genetic conditions to medical students
Vanasse, A. M., Weiler, T., Roth, E. A., Upadhya, S., Toriello, H. V., VanLeuven, A. J., Norris, J. R., Carey, J. C. & Sobering, A. K., Jan 2023, In: American Journal of Medical Genetics, Part A. 191, 1, p. 299-305 7 p.Research output: Contribution to journal › Article › peer-review
Open Access -
The Simple prEservatioN of Single cElls method for cryopreservation enables the generation of single-cell immune profiles from whole blood
Satpathy, S., Thomas, B. E., Pilcher, W. J., Bakhtiari, M., Ponder, L. A., Pacholczyk, R., Prahalad, S., Bhasin, S. S., Munn, D. H. & Bhasin, M. K., 2023, In: Frontiers in immunology. 14, 1271800.Research output: Contribution to journal › Article › peer-review
Open Access -
The Transcription Factor RXRa in CD11c+ APCs Regulates Intestinal Immune Homeostasis and Inflammation
Manoharan, I., Shanmugam, A. K., Ramalingam, M., Patel, N., Thangaraju, M., Ande, S., Pacholczyk, R., Prasad, P. D. & Manicassamy, S., Sep 20 2023, In: Journal of Immunology. 211, 5, p. 853-861 9 p.Research output: Contribution to journal › Article › peer-review
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Tumor PD-L1 engages myeloid PD-1 to suppress type I interferon to impair cytotoxic T lymphocyte recruitment
Klement, J. D., Redd, P. S., Lu, C., Merting, A. D., Poschel, D. B., Yang, D., Savage, N. M., Zhou, G., Munn, D. H., Fallon, P. G. & Liu, K., Mar 13 2023, In: Cancer Cell. 41, 3, p. 620-636.e9Research output: Contribution to journal › Article › peer-review
Open Access23 Scopus citations -
Ufmylation of UFBP1 Is Dispensable for Endoplasmic Reticulum Stress Response, Embryonic Development, and Cardiac and Intestinal Homeostasis
Tandra, V., Anderson, T., Ayala, J. D., Weintraub, N. L., Singh, N., Li, H. & Li, J., Aug 2023, In: Cells. 12, 15, 1923.Research output: Contribution to journal › Article › peer-review
Open Access -
Upregulation of the EGFR/MEK1/MAPK1/2 signaling axis as a mechanism of resistance to antiestrogen-induced BimEL dependent apoptosis in ER+ breast cancer cells
Hagan, M. L., Mander, S., Joseph, C., McGrath, M., Barrett, A., Lewis, A., Hill, W. D., Browning, D., McGee-Lawrence, M. E., Cai, H., Liu, K., Barrett, J. T., Gewirtz, D. A., Thangaraju, M. & Schoenlein, P. V., Feb 2023, In: International journal of oncology. 62, 2, 20.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Using focus groups to plan culturally acceptable primary cervical cancer screening in Grenada, West Indies
Hyacinth-Purcell, C., Sylvester-Gill, J., Sperr, E., McPherson, J. & Baldwin, A., 2023, In: Revista Panamericana de Salud Publica/Pan American Journal of Public Health. 47, e32.Research output: Contribution to journal › Article › peer-review
Open Access -
2022
2022 Association of Professors of Human and Medical Genetics (APHMG) consensus–based update of the core competencies for undergraduate medical education in genetics and genomics
Association of Professors of Human and Medical Genetics Course Directors Special Interest Group Medical Education Core Curriculum Workgroup, Oct 2022, In: Genetics in Medicine. 24, 10, p. 2167-2179 13 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
A Novel Role for RNF126 in the Promotion of G2 Arrest via Interaction With 14-3-3σ
Fa, P., Qiu, Z., Wang, Q. E., Yan, C. & Zhang, J., Feb 1 2022, In: International Journal of Radiation Oncology Biology Physics. 112, 2, p. 542-553 12 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
A novel unbalanced translocation between chromosomes 5p and 18q leading to dysmorphology and global developmental delay
Verdi, G., Li, D., Elsea, S. H., Nelson, B., Bhoj, E. J., Hakonarson, H., Yearwood, K. R., Upadhya, S., Gluschitz, S., Smith, J. L. & Sobering, A. K., Apr 2022, In: Molecular Genetics and Genomic Medicine. 10, 4, e1900.Research output: Contribution to journal › Article › peer-review
Open Access -
Article Watch: July, 2022
Slaughter, C. A., Jul 2022, In: Journal of Biomolecular Techniques. 33, 2Research output: Contribution to journal › Article › peer-review
Open Access -
A small-molecule inhibitor of MDMX suppresses cervical cancer cells via the inhibition of E6-E6AP-p53 axis
Zhang, J., Yu, G., Yang, Y., Wang, Y., Guo, M., Yin, Q., Yan, C., Tian, J., Fu, F. & Wang, H., Mar 2022, In: Pharmacological Research. 177, 106128.Research output: Contribution to journal › Article › peer-review
23 Scopus citations -
Autonomous regulation of retinal insulin biosynthesis in diabetes
Jones, M. A., Jadeja, R. N., Flandrin, O., Abdelrahman, A. A., Thounojam, M. C., Thomas, S., Dai, C., Xiao, H., Chen, J. K., Smith, S. B., Bartoli, M., Martin, P. M. & Powell, F. L., Aug 2022, In: Neuropeptides. 94, 102258.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Clinical Validation and Diagnostic Utility of Optical Genome Mapping for Enhanced Cytogenomic Analysis of Hematological Neoplasms
Sahajpal, N. S., Mondal, A. K., Tvrdik, T., Hauenstein, J., Shi, H., Deeb, K. K., Saxe, D., Hastie, A. R., Chaubey, A., Savage, N. M., Kota, V. & RAVINDRA, KOLHE., Dec 2022, In: Journal of Molecular Diagnostics. 24, 12, p. 1279-1291 13 p.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
Co-axial electrospraying of injectable multi-cancer drugs nanocapsules with polymer shells for targeting aggressive breast cancers
Khan, M., Hasan, M. M., Barnett, A., Piranlioglu, R., Rashid, M., Alptekin, A. & Arbab, A., Dec 2022, In: Cancer Nanotechnology. 13, 1, 6.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Design, Synthesis, and Molecular Docking Studies of Curcumin Hybrid Conjugates as Potential Therapeutics for Breast Cancer
Panda, S. S., Tran, Q. L., Rajpurohit, P., Pillai, G. G., Thomas, S. J., Bridges, A. E., Capito, J. E., Thangaraju, M. & Lokeshwar, B. L., Apr 6 2022, In: Pharmaceuticals. 15, 4, 451.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Design and synthesis of ibuprofen-quinoline conjugates as potential anti-inflammatory and analgesic drug candidates
Ghanim, A. M., Girgis, A. S., Kariuki, B. M., Samir, N., Said, M. F., Abdelnaser, A., Nasr, S., Bekheit, M. S., Abdelhameed, M. F., Almalki, A. J., Ibrahim, T. S. & Panda, S. S., Feb 2022, In: Bioorganic Chemistry. 119, 105557.Research output: Contribution to journal › Article › peer-review
Open Access28 Scopus citations