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Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Anterograde transport and signal regulation of GPCRs
Wu, G. (PI)
National Institute of General Medical Sciences
8/15/16 → 7/31/21
Project: Research project
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The PKCι-β-arrestin2 axis disrupts SORLA retrograde trafficking, driving its degradation and amyloid pathology in Alzheimer’s disease
Rehman, H., Yan, S., Saggu, S., Aida, M., Zhang, F., Shu, Y., Jones, A., Trang, A., Dew, E., Zhi, W., Claeboe, E. T., Baucum, A. J., Wu, G., Jiao, K. & Wang, Q., Dec 2025, In: Molecular Neurodegeneration. 20, 1, 76.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Cdk5rap3-mediated regulation of lysosomal and ER membrane proteins is pivotal for the survival and function of pancreatic acinar cells
Huang, Y., Zhou, F., Xu, X., Wang, Y., Quintero, M., Liu, S., Liu, C., Zhu, G., Cai, Y., Dong, Z., Bollag, R., Wu, G., Sabbatini, M. E. & Li, H., Aug 2025, In: American Journal of Physiology - Cell Physiology. 329, 2, p. C513-C529Research output: Contribution to journal › Article › peer-review
Open Access -
Antagonism of β-arrestins in IL-4–driven microglia reactivity via the Samd4/mTOR/OXPHOS axis in Parkinson’s disease
Liu, J., Liang, Y., Meng, Q., Chen, J., Ma, J., Zhu, H., Cai, L., Song, N., Ding, J., Fan, Y., Lu, M., Wu, G., Fang, Y. & Hu, G., Aug 2024, In: Science Advances. 10, 34, eadn4845.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Protocol to visualize and quantify the COPII concentration and anterograde transport of nascent G protein-coupled receptors
Xu, X. & Wu, G., Jun 21 2024, In: STAR Protocols. 5, 2, 102955.Research output: Contribution to journal › Article › peer-review
Open Access -
The ufmylation cascade controls COPII recruitment, anterograde transport, and sorting of nascent GPCRs at ER
Xu, X., Huang, W., Bryant, C. N., Dong, Z., Li, H. & Wu, G., Jun 2024, In: Science Advances. 10, 25, eadm9216.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations