Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
Projects
- 22 Finished
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Phosphatases in T cell regulation during autoimmunity and anti-cancer responses
Gascoigne, N. R. J. (PI)
National Research Foundation Singapore
11/1/21 → 10/31/24
Project: Research project
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Modulation of chimeric antigen receptor T cell (CAR-T) signalling to enhance anti-cancer T cell function
Gascoigne, N. R. J. (PI)
National Research Foundation Singapore
1/1/21 → 12/31/23
Project: Research project
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Modulation of chimeric antigen receptor T cell (CAR-T) signalling to enhance anti-cancer T cell function
Gascoigne, N. R. J. (PI)
1/1/21 → 12/31/23
Project: Research project
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New MHC technologies to identify and analyze SARS-CoV-2-specific CD8+ T cells
Gascoigne, N. R. J. (PI)
National Research Foundation Singapore
8/1/20 → 7/31/21
Project: Research project
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Singapore Initiative in Next Generation T-cell Decoding for Immunotherapy (SiT-Decode)
Gascoigne, N. R. J. (PI)
National Research Foundation Singapore
7/1/18 → 6/30/21
Project: Research project
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Spatial cartography of human thymus enables the geopositioning of lineage transcription factors in rare mimetic thymic epithelial cells
Kamaraj, U. S., Chen, Y., Lei, J., Gautam, P., Horcharoensuk, P., Clemente, C. K. M., Weinacht, K. G., Gascoigne, N. R. J., Chen, J., Chen, C. K., Chen, Q., Li, Q. J., Ng, L. G. & Loh, Y. H., Dec 2026, In: Nature communications. 17, 1, 3721.Research output: Contribution to journal › Article › peer-review
Open Access -
Tuning the sensitivity of mechanosensory receptors through histidine scanning
Wang, Y., Wang, Y., Yuan, W., Fan, M., Wang, X., Wang, A., Bao, Y., Zhang, Y., Tan, J. C., Wang, J., Liu, J., Huang, T., Han, Z., Pei, B., Chen, L., Ren, Z., Wang, X., Hu, L., Wu, S. & Pang, M. & 14 others, , Mar 19 2026, In: Cell. 189, 6, p. 1680-1700.e48Research output: Contribution to journal › Article › peer-review
1 Link opens in a new tab Scopus citations -
Occlusion of TCR binding to HLA-A*11:01 by a non-pathogenic human alloantibody
Hamidinia, M., Gu, Y., Ser, Z., Brzostek, J., Tay, N. Q., Yap, J., Chua, Y. L., Lim, Y. T., Wood, K. J., Vathsala, A., Sobota, R. M., MacAry, P. A. & Gascoigne, N. R. J., Dec 2025, In: Cellular and Molecular Life Sciences. 82, 1, 94.Research output: Contribution to journal › Article › peer-review
Open Access -
Non-viral, high throughput genetic engineering of primary immune cells using nanostraw-mediated transfection
Kumar, A. R. K., Low, J., Lim, J., Myint, B., Sun, X., Wu, L., Cheng, H. S., Yip, S., Ming Cheng, C. Z., Manoharan, T., Quek, Y. J., Shou, Y., Tian, J. S., Ng, Y. Y., Gascoigne, N. R. J., Tan, N. S., Sugimura, R., Chia, G., Sze Cheung, A. M. & Yawata, M. & 1 others, , Jun 2025, In: Biomaterials. 317, 123079.Research output: Contribution to journal › Article › peer-review
15 Link opens in a new tab Scopus citations -
Protocol for the simultaneous activation and lentiviral transduction of primary human T cells with artificial T cell receptors
Tan, J. Y. M., Tan, J. C., Wang, C., Wu, L., Gascoigne, N. R. J. & Bhatt, S., Mar 21 2025, In: STAR Protocols. 6, 1, 103685.Research output: Contribution to journal › Article › peer-review
Open Access3 Link opens in a new tab Scopus citations