Projects per year
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Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Critical role of NRF2 in globin gene regulation in sickle cell disease mouse models
Zhu, X. (PI)
Project: Research project
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Critical role of NRF2 in globin gene regulation in sickle cell disease mouse models
Zhu, X. (PI)
National Institute of Diabetes and Digestive and Kidney Diseases
9/17/19 → 6/30/22
Project: Research project
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Simvastatin-Mediated Nrf2 Activation Induces Fetal Hemoglobin and Antioxidant Enzyme Expression to Ameliorate the Phenotype of Sickle Cell Disease
Xi, C., Palani, C., Takezaki, M., Shi, H., Horuzsko, A., Pace, B. S. & Zhu, X., Mar 2024, In: Antioxidants. 13, 3, 337.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Bach1 inhibitor HPP-D mediates γ-globin gene activation in sickle erythroid progenitors
Palani, C. D., Zhu, X., Alagar, M., Attucks, O. C. & Pace, B. S., Jan 2024, In: Blood Cells, Molecules, and Diseases. 104, 102792.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Nrf2 Drives Hepatocellular Carcinoma Progression through Acetyl-CoA-Mediated Metabolic and Epigenetic Regulatory Networks
Xi, C., Pang, J., Barrett, A., Horuzsko, A., Ande, S., Mivechi, N. F. & Zhu, X., Oct 1 2023, In: Molecular Cancer Research. 21, 10, p. 1079-1092 14 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Nrf2 sensitizes ferroptosis through L-2-hydroxyglutarate–mediated chromatin modifications in sickle cell disease
Xi, C., Pang, J., Zhi, W., Chang, C. S. S., Siddaramappa, U., Shi, H., Horuzsko, A., Pace, B. S. & Zhu, X., Jul 27 2023, In: Blood. 142, 4, p. 382-396 15 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
Novel histone deacetylase inhibitor CT-101 induces γ-globin gene expression in sickle erythroid progenitors with targeted epigenetic effects
Junker, L. H., Li, B., Zhu, X., Koti, S., Cerbone, R. E., Hendrick, C. L., Sangerman, J., Perrine, S. & Pace, B. S., Mar 2022, In: Blood Cells, Molecules, and Diseases. 93, 102626.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations