Project Details
Description
ABSTRACT
Our long term goal is to identify and characterize genetic mutations involved in the pathogenesis of
keratoconus (KC). KC is a bilateral, asymmetric corneal degeneration characterized by localized thinning and
protrusion of the thinned cornea. KC leads to high myopia, irregular astigmatism, and cornea scarring.
Although genetic factors contribute to KC pathogenesis, its genetic causes remain to be identified. Only
mutations in the VSX1 and MIR184 genes are known to cause KC, but they account for
Status | Finished |
---|---|
Effective start/end date | 5/1/13 → 4/30/24 |
Funding
- National Eye Institute: $364,307.00
- National Eye Institute: $435,422.00
- National Eye Institute: $423,045.00
- National Eye Institute: $31,031.00
- National Eye Institute: $382,328.00
- National Eye Institute: $434,017.00
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