Project Details
Description
DESCRIPTION: Neuroblastoma (NB) is the most common solid tumor in children
and accounts for 15% of all childhood cancer deaths. Inheritance has been
implicated in NB although the location of predisposing gene(s) has not been
identified. Constitutional translocations have been valuable tools for gene
discovery in a large number of human diseases, where it has been shown
repeatedly that the interrupted gene is responsible for the disease. The PI
has identified 2 NB subjects with constitutional translocations. The goal
of the proposed work is to characterize the breakpoints and identify the
genes disrupted by the translocations.
| Status | Finished |
|---|---|
| Effective start/end date | 1/1/97 → 3/31/06 |
Funding
- National Institute of Neurological Disorders and Stroke
ASJC
- Medicine(all)
- Neuroscience(all)
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