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Targeting neuropilin-1 in human leukemia and lymphoma
Karjalainen, K., Jaalouk, D. E., Bueso-Ramos, C. E., Zurita, A. J., Kuniyasu, A., Eckhardt, B. L., Marini, F. C., Lichtiger, B., O'Brien, S., Kantarjian, H. M., Cortes, J. E., Koivunen, E., Arap, W. & Pasqualini, R., Jan 20 2011, In: Blood. 117, 3, p. 920-927 8 p.Research output: Contribution to journal › Article › peer-review
87 Scopus citations -
Targeting Neph1 and ZO-1 protein-protein interaction in podocytes prevents podocyte injury and preserves glomerular filtration function
Sagar, A., Arif, E., Solanki, A. K., Srivastava, P., Janech, M. G., Kim, S. H., Lipschutz, J. H., Kwon, S. H., Ashish & Nihalani, D., Dec 1 2017, In: Scientific reports. 7, 1, 12047.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
Targeting neovascularization in ischemic retinopathy: Recent advances
Al-Shabrawey, M., Elsherbiny, M., Nussbaum, J., Othman, A., Megyerdi, S. & Tawfik, A., Jun 2013, In: Expert Review of Ophthalmology. 8, 3, p. 267-286 20 p.Research output: Contribution to journal › Review article › peer-review
33 Scopus citations -
Targeting neddylation E2 for anticancer therapy, putting new wine into new bottles?
Zou, J. & Su, H., Jul 2019, In: EBioMedicine. 45, p. 3-4 2 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access1 Scopus citations -
Targeting mucosal addressin cellular adhesion molecule (MAdCAM)-1 to noninvasively image experimental Crohn's disease
Bachmann, C., Klibanov, A. L., Olson, T. S., Sonnenschein, J. R., Rivera-Nieves, J., Cominelli, F., Ley, K. F., Lindner, J. R. & Pizarro, T. T., Jan 2006, In: Gastroenterology. 130, 1, p. 8-16 9 p.Research output: Contribution to journal › Article › peer-review
34 Scopus citations -
Targeting mitochondrial metabolism in prostate cancer with triterpenoids
Mamouni, K., Kallifatidis, G. & Lokeshwar, B. L., Mar 1 2021, In: International journal of molecular sciences. 22, 5, p. 1-15 15 p., 2466.Research output: Contribution to journal › Review article › peer-review
Open Access14 Scopus citations -
Targeting metastatic breast cancer with ANG1005, a novel peptide-paclitaxel conjugate that crosses the blood-brain-barrier (BBB)
Li, F. & Tang, S. C., Mar 1 2017, In: Genes and Diseases. 4, 1, p. 1-3 3 p.Research output: Contribution to journal › Editorial › peer-review
Open Access22 Scopus citations -
Targeting MET and EGFR crosstalk signaling in triple-negative breast cancers
Linklater, E. S., Tovar, E. A., Essenburg, C. J., Turner, L., Madaj, Z., Winn, M. E., Melnik, M. K., Korkaya, H., Maroun, C. R., Christensen, J. G., Steensma, M. R., Boerner, J. L. & Graveel, C. R., 2016, In: Oncotarget. 7, 43, p. 69903-69915 13 p.Research output: Contribution to journal › Article › peer-review
Open Access40 Scopus citations -
Targeting lymphotoxin β receptor with tumor-specific T lymphocytes for tumor regression
Yang, D., Ud Din, N., Browning, D. D., Abrams, S. I. & Liu, K., Sep 1 2007, In: Clinical Cancer Research. 13, 17, p. 5202-5210 9 p.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
Targeting intrinsically disordered regions facilitates discovery of calcium channels 3.2 inhibitory peptides for adeno-associated virus-mediated peripheral analgesia
Shin, S. M., Lauzadis, J., Itson-Zoske, B., Cai, Y., Fan, F., Natarajan, G. K., Kwok, W. M., Puopolo, M., Hogan, Q. H. & Yu, H., Dec 1 2022, In: Pain. 163, 12, p. 2466-2484 19 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Targeting insomnia symptoms as a path to reduction of suicide risk: the role of cognitive behavioral therapy for insomnia (CBT-I): the role of cognitive behavioral therapy for insomnia (CBT-I)
McCall, W. V., Dec 12 2022, In: Sleep. 45, 12Research output: Contribution to journal › Article › peer-review
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Targeting IL11 receptor in leukemia and lymphoma: A functional ligand-directed study and hematopathology analysis of patient-derived specimens
Karjalainen, K., Jaalouk, D. E., Bueso-Ramos, C., Bover, L., Sun, Y., Kuniyasu, A., Driessen, W. H. P., Cardó-Vila, M., Rietz, C., Zurita, A. J., O'Brien, S., Kantarjian, H. M., Cortes, J. E., Calin, G. A., Koivunen, E., Arap, W. & Pasqualini, R., Jul 1 2015, In: Clinical Cancer Research. 21, 13, p. 3041-3051 11 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Targeting hypoxia-driven metabolic reprogramming to constrain tumor progression and metastasis
Miranda-Galvis, M. & Teng, Y., Aug 1 2020, In: International journal of molecular sciences. 21, 15, p. 1-17 17 p., 5487.Research output: Contribution to journal › Review article › peer-review
Open Access20 Scopus citations -
Targeting hyaluronidase for cancer therapy: Antitumor activity of sulfated hyaluronic acid in prostate cancer cells
Benitez, A., Yates, T. J., Lopez, L. E., Cerwinka, W. H., Bakkar, A. & Lokeshwar, V. B., Jun 15 2011, In: Cancer Research. 71, 12, p. 4085-4095 11 p.Research output: Contribution to journal › Article › peer-review
112 Scopus citations -
Targeting hyaluronic acid synthase-3 (HAS3) for the treatment of advanced renal cell carcinoma
Wang, J., Jordan, A. R., Zhu, H., Hasanali, S. L., Thomas, E., Lokeshwar, S. D., Morera, D. S., Alexander, S., McDaniels, J., Sharma, A., Aguilar, K., Sarcan, S., Zhu, T., Soloway, M. S., Terris, M. K., Thangaraju, M., Lopez, L. E. & Lokeshwar, V. B., Dec 2022, In: Cancer Cell International. 22, 1, 421.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Targeting hyaluronic acid family for cancer chemoprevention and therapy
Lokeshwar, V. B., Mirza, S. & Jordan, A., 2014, Advances in Cancer Research. Academic Press Inc., p. 35-65 31 p. (Advances in Cancer Research; vol. 123).Research output: Chapter in Book/Report/Conference proceeding › Chapter
110 Scopus citations -
Targeting HSF1 disrupts HSP90 chaperone function in chronic lymphocytic leukemia
Ganguly, S., Home, T., Yacoub, A., Kambhampati, S., Shi, H., Dandawate, P., Padhye, S., Saluja, A. K., McGuirk, J. & Rao, R., 2015, In: Oncotarget. 6, 31, p. 31767-31779 13 p.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations -
Targeting histone deacetylase 6 mediates a dual anti-melanoma effect: Enhanced antitumor immunity and impaired cell proliferation
Woan, K. V., Lienlaf, M., Perez-Villaroel, P., Lee, C., Cheng, F., Knox, T., Woods, D. M., Barrios, K., Powers, J., Sahakian, E., Wang, H. W., Canales, J., Marante, D., Smalley, K. S. M., Bergman, J., Seto, E., Kozikowski, A., Pinilla-Ibarz, J., Sarnaik, A., Celis, E., & 3 others , Aug 1 2015, In: Molecular Oncology. 9, 7, p. 1447-1457 11 p.Research output: Contribution to journal › Article › peer-review
Open Access89 Scopus citations -
Targeting HER-3 to elicit antitumor helper T cells against head and neck squamous cell carcinoma
Kumai, T., Ohkuri, T., Nagato, T., Matsuda, Y., Oikawa, K., Aoki, N., Kimura, S., Celis, E., Harabuchi, Y. & Kobayashi, H., Nov 5 2015, In: Scientific reports. 5, 16280.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
Targeting Genetic Modifiers of HBG Gene Expression in Sickle Cell Disease: The miRNA Option
Starlard-Davenport, A., Gu, Q. & Pace, B. S., Sep 2022, In: Molecular Diagnosis and Therapy. 26, 5, p. 497-509 13 p.Research output: Contribution to journal › Review article › peer-review
Open Access4 Scopus citations -
Targeting FGFR1 to suppress leukemogenesis in syndromic and de novo AML in murine models
Wu, Q., Bhole, A., Qin, H., Karp, J., Malek, S., Cowell, J. K. & Ren, M., 2016, In: Oncotarget. 7, 31, p. 49733-49742 10 p.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
Targeting Fc Receptor-Mediated Effects and the “Don’t Eat Me” Signal with an Oncolytic Virus Expressing an Anti-CD47 Antibody to Treat Metastatic Ovarian Cancer
Tian, L., Xu, B., Teng, K. Y., Song, M., Zhu, Z., Chen, Y., Wang, J., Zhang, J., Feng, M., Kaur, B., Rodriguez, L., Caligiuri, M. A. & Yu, J., Jan 1 2022, In: Clinical Cancer Research. 28, 1, p. 201-214 14 p.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
Targeting endothelial barrier dysfunction caused by circulating bacterial and mitochondrial n-formyl peptides with deformylase
Martinez-Quinones, P., Komic, A., McCarthy, C. G., Webb, R. C. & Wenceslau, C. F., 2019, In: Frontiers in immunology. 10, JUN, 1270.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Targeting EGFR/HER2/HER3 with a Three-in-One Aptamer-siRNA Chimera Confers Superior Activity against HER2+ Breast Cancer
Yu, X., Ghamande, S. A., Liu, H., Xue, L., Zhao, S., Tan, W., Zhao, L., Tang, S-C., Wu, D., Korkaya, H., Maihle, N. J. & Liu, H., Mar 2 2018, In: Molecular Therapy - Nucleic Acids. 10, p. 317-330 14 p.Research output: Contribution to journal › Article › peer-review
Open Access54 Scopus citations -
Targeting cholinergic system to modulate liver injury
Jadeja, R. N., Rachakonda, V. P. & Khurana, S., 2018, In: Current drug targets. 19, 8, p. 938-944 7 p.Research output: Contribution to journal › Review article › peer-review
4 Scopus citations -
Targeting Cardiovascular Adverse Events of Metastatic Renal Cell Carcinoma Therapies
Guha, A., Sayegh, N. & Agarwal, N., Jun 2022, In: JACC: CardioOncology. 4, 2, p. 235-237 3 p.Research output: Contribution to journal › Editorial › peer-review
Open Access1 Scopus citations -
Targeting breast stem cells with the cancer preventive compounds curcumin and piperine
Kakarala, M., Brenner, D. E., Korkaya, H., Cheng, C., Tazi, K., Ginestier, C., Liu, S., Dontu, G. & Wicha, M. S., Aug 2010, In: Breast Cancer Research and Treatment. 122, 3, p. 777-785 9 p.Research output: Contribution to journal › Article › peer-review
397 Scopus citations -
Targeting Bone Marrow to Potentiate the Anti-Tumor Effect of Tyrosine Kinase Inhibitor in Preclinical Rat Model of Human Glioblastoma
Shaaban, S., Alsulami, M., Arbab, S. A., Ara, R., Shankar, A., Iskander, A., Angara, K., Jain, M., Bagher-Ebadian, H., Achyut, B. R. & Arbab, A. S., Jul 19 2016, In: International Journal of Cancer Research. 12, 2, p. 69-81 13 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
Targeting autophagy in ischemic stroke: From molecular mechanisms to clinical therapeutics
Ajoolabady, A., Wang, S., Kroemer, G., Penninger, J. M., Uversky, V. N., Pratico, D., Henninger, N., Reiter, R. J., Bruno, A., Joshipura, K., Aslkhodapasandhokmabad, H., Klionsky, D. J. & Ren, J., Sep 2021, In: Pharmacology and Therapeutics. 225, 107848.Research output: Contribution to journal › Review article › peer-review
Open Access65 Scopus citations -
Targeting autophagy as a strategy for drug discovery and therapeutic modulation
Gao, L., Jauregui, C. E. & Teng, Y., Mar 2017, In: Future Medicinal Chemistry. 9, 3, p. 335-345 11 p.Research output: Contribution to journal › Review article › peer-review
27 Scopus citations -
Targeting ATGL to rescue BSCL2 lipodystrophy and its associated cardiomyopathy
Zhou, H., Lei, X., Yan, Y., Lydic, T., Li, J., Weintraub, N. L., Su, H. & Chen, W., Jul 25 2019, In: JCI Insight. 4, 14, e129781.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
Targeting a Single Codon to Rescue Septic Acute Kidney Injury
Chen, G. & Dong, Z., Feb 1 2023, In: Journal of the American Society of Nephrology. 34, 2, p. 179-181 3 p.Research output: Contribution to journal › Editorial › peer-review
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Targeting Anti-Angiogenic VEGF165b–VEGFR1 Signaling Promotes Nitric Oxide Independent Therapeutic Angiogenesis in Preclinical Peripheral Artery Disease Models
Kuppuswamy, S., Annex, B. H. & Ganta, V. C., Sep 2022, In: Cells. 11, 17, 2676.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Targeting adenoviral vectors for enhanced gene therapy of uterine leiomyomas
Nair, S., Curiel, D. T., Rajaratnam, V., Thota, C. & Al-Hendy, A., Sep 2013, In: Human Reproduction. 28, 9, p. 2398-2406 9 p.Research output: Contribution to journal › Article › peer-review
21 Scopus citations -
Targeting ABL and SRC kinases in chronic myeloid leukemia: Experience with dasatinib
Quintás-Cardama, A., Kantarjian, H. & Cortes, J., Dec 2006, In: Future Oncology. 2, 6, p. 655-665 11 p.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
targetHub: A programmable interface for miRNA-gene interactions
Manyam, G., Ivan, C., Calin, G. A. & Coombes, K. R., Oct 15 2013, In: Bioinformatics. 29, 20, p. 2657-2658 2 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Targeted ultrasound contrast agent for molecular imaging of inflammation in high-shear flow.
Klibanov, A. L., Rychak, J. J., Yang, W. C., Alikhani, S., Li, B., Acton, S., Lindner, J. R., Ley, K. & Kaul, S., Nov 2006, In: Contrast Media and Molecular Imaging. 1, 6, p. 259-266 8 p.Research output: Contribution to journal › Article › peer-review
142 Scopus citations -
Targeted therapy of human malignant glioma in a mouse model by 2-5A antisense directed against telomerase RNA
Kondo, S., Kondo, Y., Li, G., Silverman, R. H. & Cowell, J. K., Jun 25 1998, In: Oncogene. 16, 25, p. 3323-3330 8 p.Research output: Contribution to journal › Article › peer-review
76 Scopus citations -
Targeted therapy in non-small cell lung cancer
Shou-Ching, T., Aug 2004, In: Chinese Journal of Lung Cancer. 7, 4, p. 284-289 6 p.Research output: Contribution to journal › Review article › peer-review
2 Scopus citations -
Targeted therapy in chronic myeloid leukemia
Jabbour, E., Cortes, J. E., Ghanem, H., O'Brien, S. & Kantarjian, H. M., Jan 2008, In: Expert Review of Anticancer Therapy. 8, 1, p. 99-110 12 p.Research output: Contribution to journal › Review article › peer-review
22 Scopus citations -
Targeted therapy for chronic myeloid leukemia
Cardama, A. Q. & Cortes, J., Jan 1 2011, Targeted Therapy for Solid Tumors and Hematologic Malignancies. Nova Science Publishers, Inc., p. 41-56 16 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Targeted therapies in hematology and their impact on patient care: Chronic and acute myeloid leukemia
Jabbour, E., Cortes, J., Ravandi, F., O'Brien, S. & Kantarjian, H., Oct 2013, In: Seminars in Hematology. 50, 4, p. 271-283 13 p.Research output: Contribution to journal › Article › peer-review
21 Scopus citations -
Targeted Therapies in Chronic Myeloid Leukemia
Jabbour, E. & Cortes, J., Oct 30 2015, Targeted Therapy in Translational Cancer Research. Wiley-Blackwell, p. 111-120 10 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Targeted therapies for non-HPV-related head and neck cancer: challenges and opportunities in the context of predictive, preventive, and personalized medicine
Shahoumi, L. A. & Yeudall, W. A., Sep 15 2019, In: EPMA Journal. 10, 3, p. 291-305 15 p.Research output: Contribution to journal › Review article › peer-review
9 Scopus citations -
Targeted Rho-associated kinase 2 inhibition suppresses murine and human chronic GVHD through a Stat3-dependent mechanism
Flynn, R., Paz, K., Du, J., Reichenbach, D. K., Taylor, P. A., Panoskaltsis-Mortari, A., Vulic, A., Luznik, L., MacDonald, K. K. P., Hill, G. R., Nyuydzefe, M. S., Weiss, J. M., Chen, W., Trzeciak, A., Serody, J. S., Aguilar, E. G., Murphy, W. J., Maillard, I., Munn, D. H., Koreth, J., & 6 others , Apr 28 2016, In: Blood. 127, 17, p. 2144-2154 11 p.Research output: Contribution to journal › Article › peer-review
Open Access108 Scopus citations -
Targeted radiotherapy and immunotherapy of human neuroblastoma with Gd2 specific monoclonal antibodies
Cheung, N. K. V., Munn, D., Kushner, B. H., Usmani, N. & Yeh, S. D. J., 1989, In: International Journal of Radiation Applications and Instrumentation.. 16, 2, p. 111-117,119-120Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Targeted pretransplant host lymphocyte depletion prior to T-cell depleted reduced-intensity allogeneic stem cell transplantation
Bishop, M. R., Steinberg, S. M., Gress, R. E., Hardy, N. M., Marchigiani, D., Kasten-Sportes, C., Dean, R., Pavletic, S. Z., Gea-Banacloche, J., Castro, K., Hakim, F., Krumlauf, M., Read, E. J., Carter, C., Leitman, S. F. & Fowler, D. H., Sep 2004, In: British Journal of Haematology. 126, 6, p. 837-843 7 p.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
Targeted overexpression of inducible 6-phosphofructo-2-kinase in adipose tissue increases fat deposition but protects against diet-induced insulin resistance and inflammatory responses
Huo, Y., Guo, X., Li, H., Xu, H., Halim, V., Zhang, W., Wang, H., Fan, Y. Y., Ong, K. T., Woo, S. L., Chapkin, R. S., Mashek, D. G., Chen, Y., Dong, H., Lu, F., Wei, L. & Wu, C., Jun 15 2012, In: Journal of Biological Chemistry. 287, 25, p. 21492-21500 9 p.Research output: Contribution to journal › Article › peer-review
46 Scopus citations -
Targeted next generation sequencing approach identifies eighteen new candidate genes in normosmic hypogonadotropic hypogonadism and Kallmann syndrome
Quaynor, S. D., Bosley, M. E., Duckworth, C. G., Porter, K. R., Kim, S. H., Kim, H. G., Chorich, L. P., Sullivan, M. E., Choi, J. H., Cameron, R. S. & Layman, L. C., Dec 5 2016, In: Molecular and Cellular Endocrinology. 437, p. 86-96 11 p.Research output: Contribution to journal › Article › peer-review
48 Scopus citations -
Targeted labeling of neurons in a specific functional micro-domain of the neocortex by combining intrinsic signal and two-photon imaging.
O'Herron, P., Shen, Z., Lu, Z., Schramm, A. E., Levy, M. & Kara, P., 2012, In: Journal of visualized experiments : JoVE. 70, p. e50025Research output: Contribution to journal › Article › peer-review
10 Scopus citations