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Targeted next generation sequencing approach identifies eighteen new candidate genes in normosmic hypogonadotropic hypogonadism and Kallmann syndrome
Quaynor, S. D., Bosley, M. E., Duckworth, C. G., Porter, K. R., Kim, S. H., Kim, H. G., Chorich, L. P., Sullivan, M. E., Choi, J. H., Cameron, R. S. & Layman, L. C., Dec 5 2016, In: Molecular and Cellular Endocrinology. 437, p. 86-96 11 p.Research output: Contribution to journal › Article › peer-review
48 Scopus citations -
Targeted overexpression of inducible 6-phosphofructo-2-kinase in adipose tissue increases fat deposition but protects against diet-induced insulin resistance and inflammatory responses
Huo, Y., Guo, X., Li, H., Xu, H., Halim, V., Zhang, W., Wang, H., Fan, Y. Y., Ong, K. T., Woo, S. L., Chapkin, R. S., Mashek, D. G., Chen, Y., Dong, H., Lu, F., Wei, L. & Wu, C., Jun 15 2012, In: Journal of Biological Chemistry. 287, 25, p. 21492-21500 9 p.Research output: Contribution to journal › Article › peer-review
46 Scopus citations -
Targeted pretransplant host lymphocyte depletion prior to T-cell depleted reduced-intensity allogeneic stem cell transplantation
Bishop, M. R., Steinberg, S. M., Gress, R. E., Hardy, N. M., Marchigiani, D., Kasten-Sportes, C., Dean, R., Pavletic, S. Z., Gea-Banacloche, J., Castro, K., Hakim, F., Krumlauf, M., Read, E. J., Carter, C., Leitman, S. F. & Fowler, D. H., Sep 2004, In: British Journal of Haematology. 126, 6, p. 837-843 7 p.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
Targeted radiotherapy and immunotherapy of human neuroblastoma with Gd2 specific monoclonal antibodies
Cheung, N. K. V., Munn, D., Kushner, B. H., Usmani, N. & Yeh, S. D. J., 1989, In: International Journal of Radiation Applications and Instrumentation.. 16, 2, p. 111-117,119-120Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Targeted Rho-associated kinase 2 inhibition suppresses murine and human chronic GVHD through a Stat3-dependent mechanism
Flynn, R., Paz, K., Du, J., Reichenbach, D. K., Taylor, P. A., Panoskaltsis-Mortari, A., Vulic, A., Luznik, L., MacDonald, K. K. P., Hill, G. R., Nyuydzefe, M. S., Weiss, J. M., Chen, W., Trzeciak, A., Serody, J. S., Aguilar, E. G., Murphy, W. J., Maillard, I., Munn, D. H., Koreth, J., & 6 others , Apr 28 2016, In: Blood. 127, 17, p. 2144-2154 11 p.Research output: Contribution to journal › Article › peer-review
Open Access108 Scopus citations -
Targeted therapies in hematology and their impact on patient care: Chronic and acute myeloid leukemia
Jabbour, E., Cortes, J., Ravandi, F., O'Brien, S. & Kantarjian, H., Oct 2013, In: Seminars in Hematology. 50, 4, p. 271-283 13 p.Research output: Contribution to journal › Article › peer-review
21 Scopus citations -
Targeted therapy of human malignant glioma in a mouse model by 2-5A antisense directed against telomerase RNA
Kondo, S., Kondo, Y., Li, G., Silverman, R. H. & Cowell, J. K., Jun 25 1998, In: Oncogene. 16, 25, p. 3323-3330 8 p.Research output: Contribution to journal › Article › peer-review
76 Scopus citations -
Targeted ultrasound contrast agent for molecular imaging of inflammation in high-shear flow.
Klibanov, A. L., Rychak, J. J., Yang, W. C., Alikhani, S., Li, B., Acton, S., Lindner, J. R., Ley, K. & Kaul, S., Nov 2006, In: Contrast Media and Molecular Imaging. 1, 6, p. 259-266 8 p.Research output: Contribution to journal › Article › peer-review
142 Scopus citations -
targetHub: A programmable interface for miRNA-gene interactions
Manyam, G., Ivan, C., Calin, G. A. & Coombes, K. R., Oct 15 2013, In: Bioinformatics. 29, 20, p. 2657-2658 2 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Targeting ABL and SRC kinases in chronic myeloid leukemia: Experience with dasatinib
Quintás-Cardama, A., Kantarjian, H. & Cortes, J., Dec 2006, In: Future Oncology. 2, 6, p. 655-665 11 p.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
Targeting adenoviral vectors for enhanced gene therapy of uterine leiomyomas
Nair, S., Curiel, D. T., Rajaratnam, V., Thota, C. & Al-Hendy, A., Sep 2013, In: Human Reproduction. 28, 9, p. 2398-2406 9 p.Research output: Contribution to journal › Article › peer-review
21 Scopus citations -
Targeting Anti-Angiogenic VEGF165b–VEGFR1 Signaling Promotes Nitric Oxide Independent Therapeutic Angiogenesis in Preclinical Peripheral Artery Disease Models
Kuppuswamy, S., Annex, B. H. & Ganta, V. C., Sep 2022, In: Cells. 11, 17, 2676.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Targeting ATGL to rescue BSCL2 lipodystrophy and its associated cardiomyopathy
Zhou, H., Lei, X., Yan, Y., Lydic, T., Li, J., Weintraub, N. L., Su, H. & Chen, W., Jul 25 2019, In: JCI Insight. 4, 14, e129781.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
Targeting Bone Marrow to Potentiate the Anti-Tumor Effect of Tyrosine Kinase Inhibitor in Preclinical Rat Model of Human Glioblastoma
Shaaban, S., Alsulami, M., Arbab, S. A., Ara, R., Shankar, A., Iskander, A., Angara, K., Jain, M., Bagher-Ebadian, H., Achyut, B. R. & Arbab, A. S., Jul 19 2016, In: International Journal of Cancer Research. 12, 2, p. 69-81 13 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
Targeting breast stem cells with the cancer preventive compounds curcumin and piperine
Kakarala, M., Brenner, D. E., Korkaya, H., Cheng, C., Tazi, K., Ginestier, C., Liu, S., Dontu, G. & Wicha, M. S., Aug 2010, In: Breast Cancer Research and Treatment. 122, 3, p. 777-785 9 p.Research output: Contribution to journal › Article › peer-review
397 Scopus citations -
Targeting EGFR/HER2/HER3 with a Three-in-One Aptamer-siRNA Chimera Confers Superior Activity against HER2+ Breast Cancer
Yu, X., Ghamande, S. A., Liu, H., Xue, L., Zhao, S., Tan, W., Zhao, L., Tang, S-C., Wu, D., Korkaya, H., Maihle, N. J. & Liu, H., Mar 2 2018, In: Molecular Therapy - Nucleic Acids. 10, p. 317-330 14 p.Research output: Contribution to journal › Article › peer-review
Open Access54 Scopus citations -
Targeting endothelial barrier dysfunction caused by circulating bacterial and mitochondrial n-formyl peptides with deformylase
Martinez-Quinones, P., Komic, A., McCarthy, C. G., Webb, R. C. & Wenceslau, C. F., 2019, In: Frontiers in immunology. 10, JUN, 1270.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Targeting Fc Receptor-Mediated Effects and the “Don’t Eat Me” Signal with an Oncolytic Virus Expressing an Anti-CD47 Antibody to Treat Metastatic Ovarian Cancer
Tian, L., Xu, B., Teng, K. Y., Song, M., Zhu, Z., Chen, Y., Wang, J., Zhang, J., Feng, M., Kaur, B., Rodriguez, L., Caligiuri, M. A. & Yu, J., Jan 1 2022, In: Clinical Cancer Research. 28, 1, p. 201-214 14 p.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
Targeting FGFR1 to suppress leukemogenesis in syndromic and de novo AML in murine models
Wu, Q., Bhole, A., Qin, H., Karp, J., Malek, S., Cowell, J. K. & Ren, M., 2016, In: Oncotarget. 7, 31, p. 49733-49742 10 p.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
Targeting HER-3 to elicit antitumor helper T cells against head and neck squamous cell carcinoma
Kumai, T., Ohkuri, T., Nagato, T., Matsuda, Y., Oikawa, K., Aoki, N., Kimura, S., Celis, E., Harabuchi, Y. & Kobayashi, H., Nov 5 2015, In: Scientific reports. 5, 16280.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
Targeting histone deacetylase 6 mediates a dual anti-melanoma effect: Enhanced antitumor immunity and impaired cell proliferation
Woan, K. V., Lienlaf, M., Perez-Villaroel, P., Lee, C., Cheng, F., Knox, T., Woods, D. M., Barrios, K., Powers, J., Sahakian, E., Wang, H. W., Canales, J., Marante, D., Smalley, K. S. M., Bergman, J., Seto, E., Kozikowski, A., Pinilla-Ibarz, J., Sarnaik, A., Celis, E., & 3 others , Aug 1 2015, In: Molecular Oncology. 9, 7, p. 1447-1457 11 p.Research output: Contribution to journal › Article › peer-review
Open Access91 Scopus citations -
Targeting HSF1 disrupts HSP90 chaperone function in chronic lymphocytic leukemia
Ganguly, S., Home, T., Yacoub, A., Kambhampati, S., Shi, H., Dandawate, P., Padhye, S., Saluja, A. K., McGuirk, J. & Rao, R., 2015, In: Oncotarget. 6, 31, p. 31767-31779 13 p.Research output: Contribution to journal › Article › peer-review
Open Access23 Scopus citations -
Targeting hyaluronic acid synthase-3 (HAS3) for the treatment of advanced renal cell carcinoma
Wang, J., Jordan, A. R., Zhu, H., Hasanali, S. L., Thomas, E., Lokeshwar, S. D., Morera, D. S., Alexander, S., McDaniels, J., Sharma, A., Aguilar, K., Sarcan, S., Zhu, T., Soloway, M. S., Terris, M. K., Thangaraju, M., Lopez, L. E. & Lokeshwar, V. B., Dec 2022, In: Cancer Cell International. 22, 1, 421.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Targeting hyaluronidase for cancer therapy: Antitumor activity of sulfated hyaluronic acid in prostate cancer cells
Benitez, A., Yates, T. J., Lopez, L. E., Cerwinka, W. H., Bakkar, A. & Lokeshwar, V. B., Jun 15 2011, In: Cancer Research. 71, 12, p. 4085-4095 11 p.Research output: Contribution to journal › Article › peer-review
112 Scopus citations -
Targeting IL11 receptor in leukemia and lymphoma: A functional ligand-directed study and hematopathology analysis of patient-derived specimens
Karjalainen, K., Jaalouk, D. E., Bueso-Ramos, C., Bover, L., Sun, Y., Kuniyasu, A., Driessen, W. H. P., Cardó-Vila, M., Rietz, C., Zurita, A. J., O'Brien, S., Kantarjian, H. M., Cortes, J. E., Calin, G. A., Koivunen, E., Arap, W. & Pasqualini, R., Jul 1 2015, In: Clinical Cancer Research. 21, 13, p. 3041-3051 11 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Targeting insomnia symptoms as a path to reduction of suicide risk: the role of cognitive behavioral therapy for insomnia (CBT-I): the role of cognitive behavioral therapy for insomnia (CBT-I)
McCall, W. V., Dec 12 2022, In: Sleep. 45, 12Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Targeting intrinsically disordered regions facilitates discovery of calcium channels 3.2 inhibitory peptides for adeno-associated virus-mediated peripheral analgesia
Shin, S. M., Lauzadis, J., Itson-Zoske, B., Cai, Y., Fan, F., Natarajan, G. K., Kwok, W. M., Puopolo, M., Hogan, Q. H. & Yu, H., Dec 1 2022, In: Pain. 163, 12, p. 2466-2484 19 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Targeting lymphotoxin β receptor with tumor-specific T lymphocytes for tumor regression
Yang, D., Ud Din, N., Browning, D. D., Abrams, S. I. & Liu, K., Sep 1 2007, In: Clinical Cancer Research. 13, 17, p. 5202-5210 9 p.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
Targeting MET and EGFR crosstalk signaling in triple-negative breast cancers
Linklater, E. S., Tovar, E. A., Essenburg, C. J., Turner, L., Madaj, Z., Winn, M. E., Melnik, M. K., Korkaya, H., Maroun, C. R., Christensen, J. G., Steensma, M. R., Boerner, J. L. & Graveel, C. R., 2016, In: Oncotarget. 7, 43, p. 69903-69915 13 p.Research output: Contribution to journal › Article › peer-review
Open Access41 Scopus citations -
Targeting mucosal addressin cellular adhesion molecule (MAdCAM)-1 to noninvasively image experimental Crohn's disease
Bachmann, C., Klibanov, A. L., Olson, T. S., Sonnenschein, J. R., Rivera-Nieves, J., Cominelli, F., Ley, K. F., Lindner, J. R. & Pizarro, T. T., Jan 2006, In: Gastroenterology. 130, 1, p. 8-16 9 p.Research output: Contribution to journal › Article › peer-review
34 Scopus citations -
Targeting Neph1 and ZO-1 protein-protein interaction in podocytes prevents podocyte injury and preserves glomerular filtration function
Sagar, A., Arif, E., Solanki, A. K., Srivastava, P., Janech, M. G., Kim, S. H., Lipschutz, J. H., Kwon, S. H., Ashish & Nihalani, D., Dec 1 2017, In: Scientific reports. 7, 1, 12047.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
Targeting neuropilin-1 in human leukemia and lymphoma
Karjalainen, K., Jaalouk, D. E., Bueso-Ramos, C. E., Zurita, A. J., Kuniyasu, A., Eckhardt, B. L., Marini, F. C., Lichtiger, B., O'Brien, S., Kantarjian, H. M., Cortes, J. E., Koivunen, E., Arap, W. & Pasqualini, R., Jan 20 2011, In: Blood. 117, 3, p. 920-927 8 p.Research output: Contribution to journal › Article › peer-review
87 Scopus citations -
Targeting nrf2-mediated gene transcription by extremely potent synthetic triterpenoids attenuate dopaminergic neurotoxicity in the MPTP mouse model of parkinson's disease
Kaidery, N. A., Banerjee, R., Yang, L., Smirnova, N. A., Hushpulian, D. M., Liby, K. T., Williams, C. R., Yamamoto, M., Kensler, T. W., Ratan, R. R., Sporn, M. B., Beal, M. F., Gazaryan, I. G. & Thomas, B., Jan 10 2013, In: Antioxidants and Redox Signaling. 18, 2, p. 139-157 19 p.Research output: Contribution to journal › Article › peer-review
129 Scopus citations -
Targeting of 12/15-Lipoxygenase in retinal endothelial cells, but not in monocytes/macrophages, attenuates high glucose-induced retinal leukostasis
Ibrahim, A. S., Saleh, H., El-Shafey, M., Hussein, K. A., El-Masry, K., Baban, B., Sheibani, N., Wang, M. H., Tawfik, A. & Al-Shabrawey, M., Jun 1 2017, In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1862, 6, p. 636-645 10 p.Research output: Contribution to journal › Article › peer-review
16 Scopus citations -
Targeting of cancer stem cell marker EpCAM by bispecific antibody EpCAMxCD3 inhibits pancreatic carcinoma
Salnikov, A. V., Groth, A., Apel, A., Kallifatidis, G., Beckermann, B. M., Khamidjanov, A., Ryschich, E., Büchler, M. W., Herr, I. & Moldenhauer, G., Sep 2009, In: Journal of Cellular and Molecular Medicine. 13, 9 B, p. 4023-4033 11 p.Research output: Contribution to journal › Article › peer-review
38 Scopus citations -
Targeting of DC-SIGN on human dendritic cells by minor fimbriated Porphyromonas gingivalis strains elicits a distinct effector T cell response
Zeituni, A. E., Jotwani, R., Carrion, J. & Cutler, C. W., Nov 1 2009, In: Journal of Immunology. 183, 9, p. 5694-5704 11 p.Research output: Contribution to journal › Article › peer-review
57 Scopus citations -
Targeting of endothelial nitric-oxide synthase to the cytoplasmic face of the Golgi complex or plasma membrane regulates Akt- versus calcium-dependent mechanisms for nitric oxide release
Fulton, D., Babbitt, R., Zoellner, S., Fontana, J., Acevedo, L., McCabe, T. J., Iwakiri, Y. & Sessa, W. C., Jul 16 2004, In: Journal of Biological Chemistry. 279, 29, p. 30349-30357 9 p.Research output: Contribution to journal › Article › peer-review
108 Scopus citations -
Targeting of pancreatic and prostate cancer stem cell characteristics by Crambe crambe marine sponge extract
Ottinger, S., Klöppel, A., Rausch, V., Liu, L., Kallifatidis, G., Gross, W., Gebhard, M. M., Brümmer, F. & Herr, I., Apr 1 2012, In: International Journal of Cancer. 130, 7, p. 1671-1681 11 p.Research output: Contribution to journal › Article › peer-review
29 Scopus citations -
Targeting phosphorylated p53 to elicit tumor-reactive T helper responses against head and neck squamous cell carcinoma
Ohara, K., Ohkuri, T., Kumai, T., Nagato, T., Nozaki, Y., Ishibashi, K., Kosaka, A., Nagata, M., Harabuchi, S., Ohara, M., Oikawa, K., Aoki, N., Harabuchi, Y., Celis, E. & Kobayashi, H., Sep 2 2018, In: OncoImmunology. 7, 9, e1466771.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Targeting PI3Kδ function for amelioration of murine chronic graft-versus-host disease
Paz, K., Flynn, R., Du, J., Tannheimer, S., Johnson, A. J., Dong, S., Stark, A. K., Okkenhaug, K., Panoskaltsis-Mortari, A., Sage, P. T., Sharpe, A. H., Luznik, L., Ritz, J., Soiffer, R. J., Cutler, C. S., Koreth, J., Antin, J. H., Miklos, D. B., MacDonald, K. P., Hill, G. R., & 10 others , Jun 2019, In: American Journal of Transplantation. 19, 6, p. 1820-1830 11 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Targeting polyamine oxidase to prevent excitotoxicity-induced retinal neurodegeneration
Pichavaram, P., Palani, C. D., Patel, C., Xu, Z., Shosha, E., Fouda, A. Y., Caldwell, R. B. & Narayanan, S. P., 2019, In: Frontiers in Neuroscience. 13, JAN, 956.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Targeting proliferative retinopathy: Arginase 1 limits vitreoretinal neovascularization and promotes angiogenic repair
Fouda, A. Y., Xu, Z., Suwanpradid, J., Rojas, M., Shosha, E., Lemtalsi, T., Patel, C., Xing, J., Zaidi, S. A., Zhi, W., Stansfield, B. K., Cheng, P. N. M., Narayanan, S. P., Caldwell, R. W. & Caldwell, R. B., Aug 2022, In: Cell Death and Disease. 13, 8, 745.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Targeting protein arginine methyltransferase 5 sensitizes glioblastoma to trametinib
Banasavadi-Siddegowda, Y. K., Namagiri, S., Otani, Y., Sur, H., Rivas, S., Bryant, J. P., Shellbourn, A., Rock, M., Chowdhury, A., Lewis, C. T., Shimizu, T., Walbridge, S., Kumarasamy, S., Shah, A. H., Lee, T. J., Maric, D., Yan, Y., Yoo, J. Y., Kumbar, S. G., Heiss, J. D., & 1 others , Jan 1 2022, In: Neuro-Oncology Advances. 4, 1, vdac095.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Targeting radioresistant breast cancer cells by single agent CHK1 inhibitor via enhancing replication stress
Zhang, Y., Lai, J., Du, Z., Gao, J., Yang, S., Gorityala, S., Xiong, X., Deng, O., Ma, Z., Yan, C., Susana, G., Xu, Y. & Zhang, J., Jun 7 2016, In: Oncotarget. 7, 23, p. 34688-34702 15 p.Research output: Contribution to journal › Article › peer-review
Open Access24 Scopus citations -
Targeting ras activity prevented amyloid beta-induced aberrant neuronal cell cycle re-entry and death
Köseoğlu, M. M., Özdilek, B. A., Djakbarova, U. & Gülüşür, A., Nov 1 2016, In: Current Alzheimer Research. 13, 11, p. 1267-1276 10 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Targeting serum glucocorticoid-regulated kinase-1 in squamous cell carcinoma of the head and neck: A novel modality of local control
Berdel, H. O., Yin, H., Liu, J. Y., Grochowska, K., Middleton, C., Yanasak, N. E., Abdelsayed, R. A., Berdel, W. E., Mozaffari, M. S., Yu, J. C. & Baban, B., Dec 8 2014, In: PloS one. 9, 12, e113795.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Targeting Squalene Epoxidase Interrupts Homologous Recombination via the ER Stress Response and Promotes Radiotherapy Efficacy
Hong, Z., Liu, T., Wan, L., Fa, P., Kumar, P., Cao, Y., Prasad, C. B., Qiu, Z., Liu, J., Wang, H., Li, Z., Wang, Q. E., Guo, P., Guo, D., Yilmaz, A. S., Lu, L., Papandreou, I., Jacob, N. K., Yan, C., Zhang, X., & 3 others , Apr 1 2022, In: Cancer Research. 82, 7, p. 1298-1312 15 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
Targeting T-cell malignancies using anti-CD4 CAR NK-92 cells
Pinz, K. G., Yakaboski, E., Jares, A., Liu, H., Firor, A. E., Chen, K. H., Wada, M., Salman, H. S., Tse, W., Hagag, N., Lan, F., Leung, E. L. H., Jiang, X. & Ma, Y., 2017, In: Oncotarget. 8, 68, p. 112783-112796 14 p.Research output: Contribution to journal › Article › peer-review
Open Access65 Scopus citations -
Targeting the DNA-binding activity of the human ERG transcription factor using new heterocyclic dithiophene diamidines
Nhili, R., Peixoto, P., Depauw, S., Flajollet, S., Dezitter, X., Munde, M. M., Ismail, M. A., Kumar, A., Farahat, A. A., Stephens, C. E., Duterque-Coquillaud, M., David Wilson, W., Boykin, D. W. & David-Cordonnier, M. H., Jan 2013, In: Nucleic Acids Research. 41, 1, p. 125-138 14 p.Research output: Contribution to journal › Article › peer-review
56 Scopus citations -
Targeting the most important complications in vascular surgery
Bennett, K. M., Kent, K. C., Schumacher, J., Greenberg, C. C. & Scarborough, J. E., Mar 1 2017, In: Journal of Vascular Surgery. 65, 3, p. 793-803 11 p.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations