A 13-year experience with epilepsy surgery

Joseph R. Smith, M. R. Lee, P. D. Jenkins, D. W. King, A. M. Murro, Y. D. Park, G. P. Lee, K. J. Meador, D. W. Loring

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


Between 1985 and 1997, 563 therapeutic craniotomies were performed: 311 anterior temporal (ATL) and 158 extramesial temporal (XMT) resections, 67 callosotomies, 20 hemispherectomies and 7 multiple subpial transections. Sixty-seven percent of nonlesional ATL cases were seizure free (SF), and 76% of nonlesional ATL cases ≤ 18 years old were SF. Seventy-eight percent of lesional ATL cases with complete resection were SF. Seventy-three percent of lesional cases ≤ 18 were SF. Thirty-seven percent of nonlesional XMT cases were SF. Seventy percent of XMT lesional cases with complete resection were SF, and 82% of lesional XMT cases ≤ 18 were SF. Of the anterior callosotomy cases, there was a ≥ 90% decrease in generalized tonic-clonic seizures in 50% of patients, and in tonic seizures, drop attacks, absence and myoclonic seizures in approximately 60-70% of patients. Of 20 hemispherectomies, 65% were SF. Of 7 multiple subpial transections, 29% were SF. Copyright (C) 2000 S. Karger AG, Basel.

Original languageEnglish (US)
Pages (from-to)98-103
Number of pages6
JournalStereotactic and Functional Neurosurgery
Issue number1-4
StatePublished - May 2000


  • Ablative surgery
  • Depth electrodes
  • Disconnective surgery
  • Drug-resistant focal epilepsy
  • Subdural electrodes

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology


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