A gene-based approach for testing association of rare alleles

Hongyan Xu, Varghese George

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Rare genetic variants have been shown to be important to the susceptibility of common human diseases. Methods for detecting association of rare genetic variants are drawing much attention. In this report, we applied a gene-based approach to the 200 simulated data sets of unrelated individuals. The test can detect the association of some genes with multiple rare variants.

Original languageEnglish (US)
Article numberS7
JournalBMC Proceedings
Issue numberSUPPL. 9
StatePublished - 2011

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)


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