@article{44aaced9a9c8443ca896baf1d237c0b0,
title = "A hypothesis concerning the general basis of organogenetic congenital anomalies",
abstract = "Evidence supports the idea that it is the degree of metabolic imbalance present in diabetic gravid women during the period of organogenesis that accounts for organogenetic congenital defects. In light of the proved and inferred metabolic instability occurring during early pregnancy, we propose that metabolic imbalances may occur that result in organogenetic congenital defects in offspring of apparently normal gravid women.",
keywords = "Organogenesis, birth defect, diabetes mellitus",
author = "Frederick Naftolin and Diamond, {Michael P.} and Emese Pinter and Reece, {E. Albert} and Sanyal, {M. K.}",
note = "Funding Information: From the Department of Obstetrics and Gynecology, Yale University School of Medicine. Supported by the March of Dimes Birth Defects Foundation, the Ju-venile Diabetes Foundation, the American Diabetes Foundation, and the National Institutes of Health. Presented in part at the Obstetrical Society of Philadelphia, March 13, 1986. Reprint requests: Frederick Naftolin, M.D., D.Phil., Department of Obstetrics and Gynecology, Yale University School of Medicine, 333 Cedar St. PO Box 3333, New Haven, CT 06510-8063. *Mellon Fellow in the Reproductive Sciences. **James Hudson Brown Scholar.",
year = "1987",
doi = "10.1016/S0002-9378(87)80332-0",
language = "English (US)",
volume = "157",
pages = "1--4",
journal = "American journal of obstetrics and gynecology",
issn = "0002-9378",
publisher = "Mosby Inc.",
number = "1",
}