A nanoleakage perspective on bonding to oxidized dentin

C. K.Y. Yiu, F. García-Godoy, F. R. Tay, D. H. Pashley, S. Imazato, N. M. King, S. C.N. Lai

Research output: Contribution to journalArticlepeer-review

73 Scopus citations


The mechanism responsible for sodium-hypochlorite-induced reduction in dentin bond strength and its reversal with reducing agents is unknown. This study examined the relationship between nanoleakage and reversal of compromised bonding to oxidized dentin. Acid-etched dentin was completely depleted of demineralized collagen matrix when sodium hypochlorite was used. Specimens were bonded with two single-bottle dentin adhesives. They were immersed in ammoniacal silver nitrate for 24 hrs before being processed for transmission electron microscopy. For both adhesives, tensile bond strengths of acid-etched dentin were significantly reduced after sodium hypochlorite treatment, but were reversed when sodium ascorbate was used. After sodium hypochlorite application, reticular nanoleakge patterns in hybrid layers were replaced by vertical, shag-carpet-like patterns along the demineralization front. This type of nanoleakage was completely eliminated after sodium ascorbate treatment with the materials tested. Residual sodium hypochlorite within the porosities of mineralized dentin may result in incomplete resin polymerization, and hence compromised bond strength.

Original languageEnglish (US)
Pages (from-to)628-632
Number of pages5
JournalJournal of Dental Research
Issue number9
StatePublished - Sep 2002
Externally publishedYes

ASJC Scopus subject areas

  • Dentistry(all)


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