Abstract
A Kb-specific monoclonal antibody, 6.3.4, defining a new class I specificity, m208, reacts with some K and D region products and with a Qa determinant present on T lymphocytes but not detectable on thymocytes and B lymphocytes. The strain distribution of reactions indicates that this determinant is controlled by the Qa-Tla region, and shows no concordance with the strain distribution pattern of any of the known Qa antigens. The antibody reacts also with L cells expressing a cloned H-2b class I gene mapping in the Qa-Tla region.
Original language | English (US) |
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Pages (from-to) | 461-474 |
Number of pages | 14 |
Journal | Immunogenetics |
Volume | 19 |
Issue number | 6 |
DOIs | |
State | Published - Jun 1984 |
ASJC Scopus subject areas
- Immunology
- Genetics