A patient with concurrent primary hyperaldosteronism and adrenal insufficiency

Francisco Puentes, Thomas W. Jackson, Carlos M. Isales

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


A 73-year-old man with history of long-standing primary hyperaldosteronism developed adrenal insufficiency after he ruptured an abdominal aortic aneurysm and had a prolonged hypotensive episode. The patient presented as a diagnostic dilemma with recurrent hypotensive episodes and hypokalemia. A cosyntropin (Cortrosyn) stimulation test demonstrated a blunted cortisol response while at the same time having a suppressed plasma renin activity level and an elevated plasma aldosterone value. Diagnosis of Addison disease and concurrent primary hyperaldosteronism resulted in the patient's being treated with an unusual combination of prednisone and spironolactone followed by marked improvement in his symptoms.

Original languageEnglish (US)
Pages (from-to)344-347
Number of pages4
JournalAmerican Journal of the Medical Sciences
Issue number6
StatePublished - Dec 2004


  • Addison disease
  • Adrenal insufficiency
  • Hypokalemia
  • Hypotension
  • Primary hyperaldosteronism

ASJC Scopus subject areas

  • General Medicine


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