@article{ba877934d5ff4c408242a428a963b9db,
title = "A pilot randomized controlled trial with paroxetine for subthreshold PTSD in Operation Enduring Freedom/Operation Iraqi Freedom era veterans",
abstract = "Subthreshold posttraumatic stress disorder (PTSD) is associated with increased risk for suicidality, depression, and functional impairment. We thus conducted a small (N=12) pilot randomized controlled trial (RCT) with paroxetine for subthreshold PTSD in Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) era veterans. Hospital Anxiety and Depression Scale (HADS) scores improved by 30.4% in the paroxetine group. Paroxetine may have promise for subthreshold PTSD.",
keywords = "PTSD, Paroxetine, Subthreshold",
author = "Naylor, {Jennifer C.} and Dolber, {Trygve R.} and Strauss, {Jennifer L.} and Kilts, {Jason D.} and Strauman, {Timothy J.} and Bradford, {Daniel W.} and Szabo, {Steven T.} and Youssef, {Nagy A.} and Connor, {Kathryn M.} and Davidson, {Jonathan R.T.} and Marx, {Christine E.}",
note = "Funding Information: The authors would like to thank Gillian Parke for her meticulous assistance with data entry and organization. Dr. Marx discloses that she is a co-applicant on pending US patent applications for the use of neurosteroids and derivatives for the treatment of central nervous system disorders and for lowering cholesterol (no patents issued, no licensing in place). She is an unpaid scientific consultant for Sage Therapeutics. The remaining authors have no potential conflicts of interest related to this work to disclose. The views expressed in this manuscript are those of the authors and do not necessarily represent the views of the Department of Veterans Affairs. Funding Information: VA Mid-Atlantic Mental Illness Research, Education, and Clinical Center (MIRECC), Durham, NC; VA Advanced Research Career Development Award (CEM), Durham, NC; VA Career Development Transition Award (CEM), Durham, NC; NIH K23 MH65080 (CEM), Durham, NC; VA Career Development Award (JLS), Durham, NC. Publisher Copyright: {\textcopyright} 2012",
year = "2013",
month = apr,
day = "30",
doi = "10.1016/j.psychres.2012.11.008",
language = "English (US)",
volume = "206",
pages = "318--320",
journal = "Psychiatry Research",
issn = "0165-1781",
publisher = "Elsevier Ireland Ltd",
number = "2-3",
}
