TY - JOUR
T1 - A randomized, double-blind clinical trial comparing the effects of continuous and pulsed ultrasound in patients with chronic rhinosinusitis
AU - Ansari, Noureddin Nakhostin
AU - Fathali, Mojtaba
AU - Naghdi, Soofia
AU - Hasson, Scott
AU - Jalaie, Shohreh
AU - Rastak, Mohammad Saeed
N1 - Funding Information:
This study was supported by Tehran University of Medical Sciences (Grant 86-02-32-5609). We thank the patients.
PY - 2012/2
Y1 - 2012/2
N2 - The objective of the present study was to compare the effects of continuous ultrasound (CUS) with pulsed ultrasound (PUS) in patients with chronic rhinosinusitis (CRS). In this prospective, randomized, double-blind, parallel group study, 40 patients (10 losses) with CRS participated. Patients received either continuous or pulsed (1:9) 1 MHz ultrasound (US) using a US head of 1 cm 2 at 1 W/cm 2 and 0.5 W/cm 2 for the maxillary and frontal sinuses, respectively. Treatment was performed in 10 sessions, 3 days per week, with US given every other day. The primary outcome measure was percent improvement in the Sinusitis Symptom Score. Measurements were taken before and after 10 treatment sessions. The patients were followed up monthly for 2 months. After treatment, both groups improved significantly on the Sinusitis Symptoms Score. Patients who received PUS had significantly decreased total symptom scores compared with patients receiving CUS (mean change 9.8 vs. 5.6, p = 0.049). The percent improvement in the Sinusitis Symptom Score between the PUS group (65.2 SD 23.1) and the CUS group (43.9 SD 40.7) was not statistically significant ( p = 0.09). The effect size for each treatment was large; PUS: d = 3.92 and CUS: d = 1.93. Symptom improvement in both groups was similar at the 2-month follow-up. These results support the use of therapeutic US for CRS. This pilot study gives only marginal evidence to favor PUS over CUS.
AB - The objective of the present study was to compare the effects of continuous ultrasound (CUS) with pulsed ultrasound (PUS) in patients with chronic rhinosinusitis (CRS). In this prospective, randomized, double-blind, parallel group study, 40 patients (10 losses) with CRS participated. Patients received either continuous or pulsed (1:9) 1 MHz ultrasound (US) using a US head of 1 cm 2 at 1 W/cm 2 and 0.5 W/cm 2 for the maxillary and frontal sinuses, respectively. Treatment was performed in 10 sessions, 3 days per week, with US given every other day. The primary outcome measure was percent improvement in the Sinusitis Symptom Score. Measurements were taken before and after 10 treatment sessions. The patients were followed up monthly for 2 months. After treatment, both groups improved significantly on the Sinusitis Symptoms Score. Patients who received PUS had significantly decreased total symptom scores compared with patients receiving CUS (mean change 9.8 vs. 5.6, p = 0.049). The percent improvement in the Sinusitis Symptom Score between the PUS group (65.2 SD 23.1) and the CUS group (43.9 SD 40.7) was not statistically significant ( p = 0.09). The effect size for each treatment was large; PUS: d = 3.92 and CUS: d = 1.93. Symptom improvement in both groups was similar at the 2-month follow-up. These results support the use of therapeutic US for CRS. This pilot study gives only marginal evidence to favor PUS over CUS.
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U2 - 10.3109/09593985.2011.571751
DO - 10.3109/09593985.2011.571751
M3 - Article
C2 - 21823980
AN - SCOPUS:84855218743
SN - 0959-3985
VL - 28
SP - 85
EP - 94
JO - Physiotherapy theory and practice
JF - Physiotherapy theory and practice
IS - 2
ER -