A role for myokines in muscle-bone interactions

Research output: Contribution to journalArticlepeer-review

151 Scopus citations


This review presents the hypothesis that muscle is a source of secreted factors (myokines) that can influence bone mass in both positive and negative ways. Growth factor secretion by muscle may therefore be one pathway through which mechanical signals are transduced biologically.

Original languageEnglish (US)
Pages (from-to)43-47
Number of pages5
JournalExercise and Sport Sciences Reviews
Issue number1
StatePublished - Jan 2011


  • FGF-2
  • IGF-1
  • muscle injury
  • myostatin
  • periosteum

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation


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