A second family with HB minneapolis-Laos or α2β2118(GH1)phetyr

K. Kleman, B. Lubin, A. Kutlar, J. B. Wilson, B. B. Webber, T. H.J. Huisman

Research output: Contribution to journalComment/debatepeer-review

1 Scopus citations


Recently, a one-year-old /Cambodian child was admitted to the Children's Hospital Medical Center because of pneumonia and severe anemia. Hematological analyses gave these results: Hb 3.6 g/dl, MCV 50 fl, RBC 2.3 X 1012/1, free erythrocyte ptotoparphysin 351 μ100 ml RBC (normal: <100), ferritin 25 ng/ml, iron saturation 10% The child recovered after transfusion and treatment for pneumonia and for severe iron deficiency. Hemoglobin (Hb) analysis of a blood sample collected prior to transfusion, by cellulose acetate electrophoresis at alkaline pH (1), showed tow components, one Quantitation of these Hbs was by cation exchange high performance liquid chromatography (HPLC) (2); the Hb E-like component constituted 26% of the hemoglobin.

Original languageEnglish (US)
Pages (from-to)401-402
Number of pages2
Issue number4
StatePublished - 1987

ASJC Scopus subject areas

  • Genetics(clinical)
  • Biochemistry, medical
  • Hematology
  • Clinical Biochemistry


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