A software package for next-gen bisulfite sequencing data analysis

Jeong-Hyeon Choi; Dong Sung Ryu; Suhas Sureshchandra; Huidong Shi; Hwan Gue Cho

doi:10.1109/BIBMW.2011.6112561

A software package for next-gen bisulfite sequencing data analysis

Jeong-Hyeon Choi, Dong Sung Ryu, Suhas Sureshchandra, Huidong Shi, Hwan Gue Cho

Biochemistry and Molecular Biology

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Bisulfite sequencing (BS-seq) is one of the most important sequencing protocols for genome-wide DNA methylation studies. However, it causes significant challenges in computation because it converts unmethylated cytosines to thymines. This paper presents a software package to address those challenges and to provide various kinds of analysis modules, from mapping to comparing multiple samples.

Original language	English (US)
Title of host publication	2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011
Pages	1061-1062
Number of pages	2
DOIs	https://doi.org/10.1109/BIBMW.2011.6112561
State	Published - 2011
Event	2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011 - Atlanta, GA, United States Duration: Nov 12 2011 → Nov 15 2011

Publication series

Name	2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011

Other

Other	2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011
Country/Territory	United States
City	Atlanta, GA
Period	11/12/11 → 11/15/11

Keywords

DNA methylation
bisulfite sequencing
next-gen sequencing

ASJC Scopus subject areas

Biomedical Engineering
Health Informatics
Health Information Management

Access to Document

10.1109/BIBMW.2011.6112561

Cite this

Choi, J-H., Ryu, D. S., Sureshchandra, S., Shi, H., & Cho, H. G. (2011). A software package for next-gen bisulfite sequencing data analysis. In 2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011 (pp. 1061-1062). Article 6112561 (2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011). https://doi.org/10.1109/BIBMW.2011.6112561

A software package for next-gen bisulfite sequencing data analysis. / Choi, Jeong-Hyeon; Ryu, Dong Sung; Sureshchandra, Suhas et al.
2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011. 2011. p. 1061-1062 6112561 (2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Choi, J-H, Ryu, DS, Sureshchandra, S, Shi, H & Cho, HG 2011, A software package for next-gen bisulfite sequencing data analysis. in 2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011., 6112561, 2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011, pp. 1061-1062, 2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011, Atlanta, GA, United States, 11/12/11. https://doi.org/10.1109/BIBMW.2011.6112561

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abstract = "Bisulfite sequencing (BS-seq) is one of the most important sequencing protocols for genome-wide DNA methylation studies. However, it causes significant challenges in computation because it converts unmethylated cytosines to thymines. This paper presents a software package to address those challenges and to provide various kinds of analysis modules, from mapping to comparing multiple samples.",

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AB - Bisulfite sequencing (BS-seq) is one of the most important sequencing protocols for genome-wide DNA methylation studies. However, it causes significant challenges in computation because it converts unmethylated cytosines to thymines. This paper presents a software package to address those challenges and to provide various kinds of analysis modules, from mapping to comparing multiple samples.

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A software package for next-gen bisulfite sequencing data analysis

Abstract

Publication series

Other

Keywords

ASJC Scopus subject areas

Access to Document

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