Acute and sub chronic oral toxicity of Sida rhomboidea. Roxb Leaf Extract

Menaka C. Thounaojam; Ravirajsinh N. Jadeja; Dipak K. Patel; Ranjitsinh V. Devkar; A. V. Ramachandran

doi:10.2202/1553-3840.1312

Acute and sub chronic oral toxicity of Sida rhomboidea. Roxb Leaf Extract

Menaka C. Thounaojam
, Ravirajsinh N. Jadeja
, Dipak K. Patel
, Ranjitsinh V. Devkar
, A. V. Ramachandran

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

Acute and sub chronic oral administration of Sida rhomboidea.Roxb (SR) aqueous leaf extract did not register any adverse behavioral alterations or significant toxic manifestations. However, significant decrement in food intake and body weight gain along with higher plasma AST and ALT levels were recorded with a dose of 3000 mg/kg body weight. It is inferred that SR extract is non-toxic, therefore, safe for consumption.

Original language	English (US)
Article number	1
Journal	Journal of Complementary and Integrative Medicine
Volume	7
Issue number	1
DOIs	https://doi.org/10.2202/1553-3840.1312
State	Published - 2010
Externally published	Yes

Keywords

OECD
Sida rhomboidea.Roxb
Toxicology

ASJC Scopus subject areas

Complementary and alternative medicine

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10.2202/1553-3840.1312

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title = "Acute and sub chronic oral toxicity of Sida rhomboidea. Roxb Leaf Extract",

abstract = "Acute and sub chronic oral administration of Sida rhomboidea.Roxb (SR) aqueous leaf extract did not register any adverse behavioral alterations or significant toxic manifestations. However, significant decrement in food intake and body weight gain along with higher plasma AST and ALT levels were recorded with a dose of 3000 mg/kg body weight. It is inferred that SR extract is non-toxic, therefore, safe for consumption.",

keywords = "OECD, Sida rhomboidea.Roxb, Toxicology",

author = "Thounaojam, \{Menaka C.\} and Jadeja, \{Ravirajsinh N.\} and Patel, \{Dipak K.\} and Devkar, \{Ranjitsinh V.\} and Ramachandran, \{A. V.\}",

note = "Funding Information: Author Notes: The authors are grateful to University Grants Commission, New Delhi for providing financial assistance in the form of the JRFSMS scholarship and to Jai Research Foundation, Vapi, India for providing experimental animals.",

year = "2010",

doi = "10.2202/1553-3840.1312",

language = "English (US)",

volume = "7",

journal = "Journal of Complementary and Integrative Medicine",

issn = "1553-3840",

publisher = "Walter de Gruyter GmbH",

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TY - JOUR

T1 - Acute and sub chronic oral toxicity of Sida rhomboidea. Roxb Leaf Extract

AU - Thounaojam, Menaka C.

AU - Jadeja, Ravirajsinh N.

AU - Patel, Dipak K.

AU - Devkar, Ranjitsinh V.

AU - Ramachandran, A. V.

N1 - Funding Information: Author Notes: The authors are grateful to University Grants Commission, New Delhi for providing financial assistance in the form of the JRFSMS scholarship and to Jai Research Foundation, Vapi, India for providing experimental animals.

PY - 2010

Y1 - 2010

N2 - Acute and sub chronic oral administration of Sida rhomboidea.Roxb (SR) aqueous leaf extract did not register any adverse behavioral alterations or significant toxic manifestations. However, significant decrement in food intake and body weight gain along with higher plasma AST and ALT levels were recorded with a dose of 3000 mg/kg body weight. It is inferred that SR extract is non-toxic, therefore, safe for consumption.

AB - Acute and sub chronic oral administration of Sida rhomboidea.Roxb (SR) aqueous leaf extract did not register any adverse behavioral alterations or significant toxic manifestations. However, significant decrement in food intake and body weight gain along with higher plasma AST and ALT levels were recorded with a dose of 3000 mg/kg body weight. It is inferred that SR extract is non-toxic, therefore, safe for consumption.

KW - OECD

KW - Sida rhomboidea.Roxb

KW - Toxicology

UR - https://www.scopus.com/pages/publications/77649334162

UR - https://www.scopus.com/pages/publications/77649334162#tab=citedBy

U2 - 10.2202/1553-3840.1312

DO - 10.2202/1553-3840.1312

M3 - Article

AN - SCOPUS:77649334162

SN - 1553-3840

VL - 7

JO - Journal of Complementary and Integrative Medicine

JF - Journal of Complementary and Integrative Medicine

IS - 1

M1 - 1

ER -

Acute and sub chronic oral toxicity of Sida rhomboidea. Roxb Leaf Extract

Abstract

Keywords

ASJC Scopus subject areas

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