Abstract
OBJECTIVE: To evaluate the role of granulocyte colony-stimulating factor (G-CSF) as adjunctive therapy for the treatment of diabetic foot infections in non-neutropenic patients. DATA SOURCES: Clinical literature was accessed through MEDLINE (1965-April 2004). Key search terms included G-CSF, infection, and diabetes. In addition, relevant references from primary and secondary article bibliographies were extracted. DATA SYNTHESIS: Three clinical trials evaluating G-CSF for diabetic foot infections were identified. These data demonstrated positive effects of G-CSF on improvement of foot infections and risk of amputations. CONCLUSIONS: Controlled trials are necessary to validate the role of adjunctive G-CSF at reducing amputations in patients with diabetic foot infections.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 2150-2153 |
| Number of pages | 4 |
| Journal | Annals of Pharmacotherapy |
| Volume | 38 |
| Issue number | 12 |
| DOIs | |
| State | Published - Dec 2004 |
| Externally published | Yes |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Diabetic foot infections
- Granulocyte colony-stimulating factor
ASJC Scopus subject areas
- Pharmacology (medical)
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