TY - JOUR
T1 - Adult-onset amenorrhea
T2 - A study of 262 patients
AU - Reindollar, Richard H.
AU - Novak, Michael
AU - Tho, Sandra P.T.
AU - McDonough, Paul G.
PY - 1986/9
Y1 - 1986/9
N2 - A series of 262 patients with amenorrhea of adult onset are reported. Hypothalamic suppression followed by inappropriate positive feedback, and then hyperprolactinemia and ovarian failure are the most frequently encountered etiologies. Other etiologies are diverse and numerically less frequent. Amenorrhea after use of oral contraceptives, or postpill amenorrhea, occurred in 77 (29%) of all patients. The average age of presentation, prior menstrual history, associated morbidity, and subsequent reproductive potential of each diagnostic group are reported. Adult-onset amenorrhea has a less significant impact on future wellbeing than was reported for a similar-sized group of patients whose amenorrhea developed as a result of pubertal aberrancy.
AB - A series of 262 patients with amenorrhea of adult onset are reported. Hypothalamic suppression followed by inappropriate positive feedback, and then hyperprolactinemia and ovarian failure are the most frequently encountered etiologies. Other etiologies are diverse and numerically less frequent. Amenorrhea after use of oral contraceptives, or postpill amenorrhea, occurred in 77 (29%) of all patients. The average age of presentation, prior menstrual history, associated morbidity, and subsequent reproductive potential of each diagnostic group are reported. Adult-onset amenorrhea has a less significant impact on future wellbeing than was reported for a similar-sized group of patients whose amenorrhea developed as a result of pubertal aberrancy.
KW - Secondary amenorrhea
KW - postpill amenorrhea
UR - http://www.scopus.com/inward/record.url?scp=0022453704&partnerID=8YFLogxK
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U2 - 10.1016/0002-9378(86)90274-7
DO - 10.1016/0002-9378(86)90274-7
M3 - Article
C2 - 3529965
AN - SCOPUS:0022453704
SN - 0002-9378
VL - 155
SP - 531
EP - 541
JO - American journal of obstetrics and gynecology
JF - American journal of obstetrics and gynecology
IS - 3
ER -