Advances in Dental Materials through Nanotechnology: Facts, Perspectives and Toxicological Aspects

Gislaine C. Padovani, Victor P. Feitosa, Salvatore Sauro, Franklin R. Tay, Gabriela Durán, Amauri J. Paula, Nelson Durán

Research output: Contribution to journalReview articlepeer-review

140 Scopus citations


Nanotechnology is currently driving the dental materials industry to substantial growth, thus reflecting on improvements in materials available for oral prevention and treatment. The present review discusses new developments in nanotechnology applied to dentistry, focusing on the use of nanomaterials for improving the quality of oral care, the perspectives of research in this arena, and discussions on safety concerns regarding the use of dental nanomaterials. Details are provided on the cutting-edge properties (morphological, antibacterial, mechanical, fluorescence, antitumoral, and remineralization and regeneration potential) of polymeric, metallic and inorganic nano-based materials, as well as their use as nanocluster fillers, in nanocomposites, mouthwashes, medicines, and biomimetic dental materials. Nanotoxicological aspects, clinical applications, and perspectives for these nanomaterials are also discussed.

Original languageEnglish (US)
Pages (from-to)621-636
Number of pages16
JournalTrends in Biotechnology
Issue number11
StatePublished - Nov 2015


  • Dental materials
  • Dentistry
  • Nanobiotechnology
  • Nanotechnology

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering


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