TY - JOUR
T1 - Advances in Head and Neck Radiotherapy to the Mandible
AU - Ferguson, Henry W
AU - Stevens, Mark R
PY - 2007/11/1
Y1 - 2007/11/1
N2 - Management of radiation-exposed bone in the mandible is a dilemma many oral and maxillofacial surgeons must confront and manage. Current advances in radiotherapy techniques using pin-point computerized accuracy in combination with other advances, such as morphed imaging, fractionalization protocols, minimization of scatter, and pretreatment dental examinations, have greatly decreased the late effects of radiation and osteoradionecrosis. The intent of this article is to provide a brief overview of the following topics: radiotherapy physics and radiobiology, effects of radiotherapy on normal tissues, including the pathogenesis of osteoradionecrosis, and advances in contemporary radiotherapy treatment.
AB - Management of radiation-exposed bone in the mandible is a dilemma many oral and maxillofacial surgeons must confront and manage. Current advances in radiotherapy techniques using pin-point computerized accuracy in combination with other advances, such as morphed imaging, fractionalization protocols, minimization of scatter, and pretreatment dental examinations, have greatly decreased the late effects of radiation and osteoradionecrosis. The intent of this article is to provide a brief overview of the following topics: radiotherapy physics and radiobiology, effects of radiotherapy on normal tissues, including the pathogenesis of osteoradionecrosis, and advances in contemporary radiotherapy treatment.
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U2 - 10.1016/j.coms.2007.07.005
DO - 10.1016/j.coms.2007.07.005
M3 - Review article
C2 - 18088905
AN - SCOPUS:35348883610
SN - 1042-3699
VL - 19
SP - 553
EP - 563
JO - Oral and Maxillofacial Surgery Clinics of North America
JF - Oral and Maxillofacial Surgery Clinics of North America
IS - 4
ER -