Aflatoxins, Hepatitis B Virus, and Hepatocellular Carcinoma

Betty Beasley Wray

Research output: Contribution to journalLetterpeer-review

6 Scopus citations


To the Editor: Blumberg and London clearly summarized the several lines of data that support the hypothesis that primary carcinoma is related to persistent infection with hepatitis B virus (HBV) (March 26 issue).1 However, they do not discuss the very high incidence of aflatoxin contamination of foods, which occurs in many of the same areas of the world where there is a high carriage rate of HBV.2 Aflatoxins (and other mycotoxins) may have a primary or secondary role in the development of primary hepatic carcinoma. They depress cellular immunity and thus may enhance a tendency toward persistent HBV infection, or.

Original languageEnglish (US)
Number of pages1
JournalNew England Journal of Medicine
Issue number14
StatePublished - Oct 1 1981

ASJC Scopus subject areas

  • Medicine(all)


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