Aging and the muscle-bone relationship

Susan A. Novotny; Gordon L. Warren; Mark W. Hamrick

doi:10.1152/physiol.00033.2014

Aging and the muscle-bone relationship

Susan A. Novotny, Gordon L. Warren, Mark W. Hamrick

Transdisciplinary Research Initiative in Inflammaging and Brain Aging (TRIBA)

Research output: Contribution to journal › Review article › peer-review

66 Scopus citations

Abstract

Aging-induced declines in muscle size and quality are thought to contribute to catabolic alterations in bone, but changes in bone with age also profoundly alter its response to muscle-derived stimuli. This review provides an overview of some of the alterations that occur in muscle and bone with aging, and discusses the cellular and molecular mechanisms that may impact these ageassociated changes.

Original language	English (US)
Pages (from-to)	8-16
Number of pages	9
Journal	Physiology
Volume	30
Issue number	1
DOIs	https://doi.org/10.1152/physiol.00033.2014
State	Published - Jan 1 2015

ASJC Scopus subject areas

Physiology

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10.1152/physiol.00033.2014

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abstract = "Aging-induced declines in muscle size and quality are thought to contribute to catabolic alterations in bone, but changes in bone with age also profoundly alter its response to muscle-derived stimuli. This review provides an overview of some of the alterations that occur in muscle and bone with aging, and discusses the cellular and molecular mechanisms that may impact these ageassociated changes.",

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Aging and the muscle-bone relationship

Abstract

ASJC Scopus subject areas

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