Amphotericin B and combination chemotherapy in the treatment of refractory metastatic breast carcinoma and sarcoma

A. N. Krutchik; A. U. Buzdar; G. R. Blumenschein; J. G. Sinkovics

Amphotericin B and combination chemotherapy in the treatment of refractory metastatic breast carcinoma and sarcoma

A. N. Krutchik
, A. U. Buzdar
, G. R. Blumenschein
, J. G. Sinkovics

Research output: Contribution to journal › Article › peer-review

Abstract

Nineteen patients resistant to an adriamycin-containing regimen were treated with 4 days of tericin B and the same adriamycin-containing chemotherapy regimen that had been given without amphotericin B. Of the 14 evaluable patients (11 with breast carcinoma and three with sarcoma), one patient with breast carcinoma achieved a partial remission and a second patient with breast carcinoma remained stable. All other patients developed progressive disease. Both hematologic and nonhematologic toxicity were significantly increased when amphotericin B was added to chemotherapy.

Original language	English (US)
Pages (from-to)	1565-1567
Number of pages	3
Journal	Cancer Treatment Reports
Volume	62
Issue number	10
State	Published - Dec 1 1978
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

ASJC Scopus subject areas

Oncology
Cancer Research

Cite this

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title = "Amphotericin B and combination chemotherapy in the treatment of refractory metastatic breast carcinoma and sarcoma",

abstract = "Nineteen patients resistant to an adriamycin-containing regimen were treated with 4 days of tericin B and the same adriamycin-containing chemotherapy regimen that had been given without amphotericin B. Of the 14 evaluable patients (11 with breast carcinoma and three with sarcoma), one patient with breast carcinoma achieved a partial remission and a second patient with breast carcinoma remained stable. All other patients developed progressive disease. Both hematologic and nonhematologic toxicity were significantly increased when amphotericin B was added to chemotherapy.",

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T1 - Amphotericin B and combination chemotherapy in the treatment of refractory metastatic breast carcinoma and sarcoma

AU - Krutchik, A. N.

AU - Buzdar, A. U.

AU - Blumenschein, G. R.

AU - Sinkovics, J. G.

PY - 1978/12/1

Y1 - 1978/12/1

N2 - Nineteen patients resistant to an adriamycin-containing regimen were treated with 4 days of tericin B and the same adriamycin-containing chemotherapy regimen that had been given without amphotericin B. Of the 14 evaluable patients (11 with breast carcinoma and three with sarcoma), one patient with breast carcinoma achieved a partial remission and a second patient with breast carcinoma remained stable. All other patients developed progressive disease. Both hematologic and nonhematologic toxicity were significantly increased when amphotericin B was added to chemotherapy.

AB - Nineteen patients resistant to an adriamycin-containing regimen were treated with 4 days of tericin B and the same adriamycin-containing chemotherapy regimen that had been given without amphotericin B. Of the 14 evaluable patients (11 with breast carcinoma and three with sarcoma), one patient with breast carcinoma achieved a partial remission and a second patient with breast carcinoma remained stable. All other patients developed progressive disease. Both hematologic and nonhematologic toxicity were significantly increased when amphotericin B was added to chemotherapy.

UR - https://www.scopus.com/pages/publications/0018234778

UR - https://www.scopus.com/pages/publications/0018234778#tab=citedBy

M3 - Article

C2 - 709557

AN - SCOPUS:0018234778

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SP - 1565

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ER -

Amphotericin B and combination chemotherapy in the treatment of refractory metastatic breast carcinoma and sarcoma

Abstract

UN SDGs

ASJC Scopus subject areas

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