On demand, rapid Ca2+-triggered homotypic and exocytic membrane-fusion events are required to repair a torn plasma membrane, and we propose that this emergency-based fusion differs fundamentally from other rapid, triggered fusion reactions. Emergency fusion might use a specialized protein and organelle emergency response team that can simultaneously promote impromptu homotypic fusion events between organelles and exocytic fusion events along the vertices between these fusion products and the plasma membrane.
|Original language||English (US)|
|Number of pages||7|
|Journal||Nature Reviews Molecular Cell Biology|
|State||Published - Jun 2005|
ASJC Scopus subject areas
- Molecular Biology
- Cell Biology