An evaluation of a 2% erythromycin ointment in the topical therapy of acne vulgaris

Jack L. Lesher; Dan K. Chalker; J. Graham Smith; Lyn C. Guenther; Charles N. Ellis; John J. Voorhees; Alan R. Shalita; Harry C. Klauda

doi:10.1016/S0190-9622(85)70074-6

An evaluation of a 2% erythromycin ointment in the topical therapy of acne vulgaris

Jack L. Lesher, Dan K. Chalker, J. Graham Smith, Lyn C. Guenther, Charles N. Ellis, John J. Voorhees, Alan R. Shalita, Harry C. Klauda

Research output: Contribution to journal › Letter › peer-review

37 Scopus citations

Abstract

Two hundred eight patients completed a 12-week, multicenter, double-blind, controlled study comparing a 2% erythromycin ointment to its vehicle. Patients were evaluated by inflammatory lesion counts and Cook acne severity grade at the initial visit and at weeks 2, 4, 8, 10, and 12. The 2% erythromycin ointment proved to be statistically more effective than the vehicle in reducing lesion counts and acne severity grade at weeks 4, 8, 10, and 12. The ointment caused few side effects and was well tolerated by most patients.

Original language	English (US)
Pages (from-to)	526-531
Number of pages	6
Journal	Journal of the American Academy of Dermatology
Volume	12
Issue number	3
DOIs	https://doi.org/10.1016/S0190-9622(85)70074-6
State	Published - 1985
Externally published	Yes

ASJC Scopus subject areas

Dermatology

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title = "An evaluation of a 2% erythromycin ointment in the topical therapy of acne vulgaris",

abstract = "Two hundred eight patients completed a 12-week, multicenter, double-blind, controlled study comparing a 2% erythromycin ointment to its vehicle. Patients were evaluated by inflammatory lesion counts and Cook acne severity grade at the initial visit and at weeks 2, 4, 8, 10, and 12. The 2% erythromycin ointment proved to be statistically more effective than the vehicle in reducing lesion counts and acne severity grade at weeks 4, 8, 10, and 12. The ointment caused few side effects and was well tolerated by most patients.",

author = "Lesher, {Jack L.} and Chalker, {Dan K.} and Smith, {J. Graham} and Guenther, {Lyn C.} and Ellis, {Charles N.} and Voorhees, {John J.} and Shalita, {Alan R.} and Klauda, {Harry C.}",

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AU - Lesher, Jack L.

AU - Chalker, Dan K.

AU - Smith, J. Graham

AU - Guenther, Lyn C.

AU - Ellis, Charles N.

AU - Voorhees, John J.

AU - Shalita, Alan R.

AU - Klauda, Harry C.

PY - 1985

Y1 - 1985

N2 - Two hundred eight patients completed a 12-week, multicenter, double-blind, controlled study comparing a 2% erythromycin ointment to its vehicle. Patients were evaluated by inflammatory lesion counts and Cook acne severity grade at the initial visit and at weeks 2, 4, 8, 10, and 12. The 2% erythromycin ointment proved to be statistically more effective than the vehicle in reducing lesion counts and acne severity grade at weeks 4, 8, 10, and 12. The ointment caused few side effects and was well tolerated by most patients.

AB - Two hundred eight patients completed a 12-week, multicenter, double-blind, controlled study comparing a 2% erythromycin ointment to its vehicle. Patients were evaluated by inflammatory lesion counts and Cook acne severity grade at the initial visit and at weeks 2, 4, 8, 10, and 12. The 2% erythromycin ointment proved to be statistically more effective than the vehicle in reducing lesion counts and acne severity grade at weeks 4, 8, 10, and 12. The ointment caused few side effects and was well tolerated by most patients.

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An evaluation of a 2% erythromycin ointment in the topical therapy of acne vulgaris

Abstract

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