TY - JOUR
T1 - An introduction to analyzing dichotomous outcomes in a longitudinal setting
T2 - A NIDRR Traumatic Brain Injury Model Systems communication
AU - Pretz, Christopher R.
AU - Ketchum, Jessica M.
AU - Cuthbert, Jeffery P.
N1 - Publisher Copyright:
Copyright © 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins.
PY - 2014/9/1
Y1 - 2014/9/1
N2 - An untapped wealth of temporal information is captured within the Traumatic Brain Injury Model Systems National Database. Utilization of appropriate longitudinal analyses can provide an avenue toward unlocking the value of this information. This article highlights 2 statistical methods used for assessing change over time when examination of noncontinuous outcomes is of interest where this article focuses on investigation of dichotomous responses. Specifically, the intent of this article is to familiarize the rehabilitation community with the application of generalized estimating equations and generalized linear mixed models as used in longitudinal studies. An introduction to each method is provided where similarities and differences between the 2 are discussed. In addition, to reinforce the ideas and concepts embodied in each approach, we highlight each method, using examples based on data from the Rocky Mountain Regional Brain Injury System.
AB - An untapped wealth of temporal information is captured within the Traumatic Brain Injury Model Systems National Database. Utilization of appropriate longitudinal analyses can provide an avenue toward unlocking the value of this information. This article highlights 2 statistical methods used for assessing change over time when examination of noncontinuous outcomes is of interest where this article focuses on investigation of dichotomous responses. Specifically, the intent of this article is to familiarize the rehabilitation community with the application of generalized estimating equations and generalized linear mixed models as used in longitudinal studies. An introduction to each method is provided where similarities and differences between the 2 are discussed. In addition, to reinforce the ideas and concepts embodied in each approach, we highlight each method, using examples based on data from the Rocky Mountain Regional Brain Injury System.
KW - Longitudinal studies
KW - Regression analysis
KW - Rehabilitation
KW - Treatment outcome
UR - http://www.scopus.com/inward/record.url?scp=84925957151&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84925957151&partnerID=8YFLogxK
U2 - 10.1097/HTR.0000000000000025
DO - 10.1097/HTR.0000000000000025
M3 - Article
C2 - 24495920
AN - SCOPUS:84925957151
SN - 0885-9701
VL - 29
SP - E65-E71
JO - Journal of Head Trauma Rehabilitation
JF - Journal of Head Trauma Rehabilitation
IS - 5
ER -