Anatomical variations of patent foramen ovale

Hussam Suradi, Zahid Amin

Research output: Chapter in Book/Report/Conference proceedingChapter


Failure of the atrial septum primum and secundum to fuse after birth results in the persistence of foramen ovale (Patent Foramen Ovale). Variations in the atrial septal morphology of the PFO are frequent and have important technical implications on the success of transcatheter PFO closure. Patients should be carefully selected on the basis of morphology and location of the interatrial defect to minimize the rate of complications of percutaneous closure of PFO and to avoid residual shunts that can result in recurrence of symptoms. To achieve a successful, complete closure of the PFO, a detailed understanding of PFO anatomy is required. In this chapter we will review the different anatomical variations of PFO and their clinical implications.

Original languageEnglish (US)
Title of host publicationPatent Foramen Ovale
PublisherSpringer-Verlag London Ltd
Number of pages10
ISBN (Electronic)9781447149873
ISBN (Print)9781447149866
StatePublished - Jan 1 2015
Externally publishedYes


  • Atrial septal aneurysm
  • Atrial septal morphology
  • Chiari network
  • Lipomatous hypertrophy of atrial septum
  • Patent foramen ovale anatomy

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)


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