@article{bc432bea49794c9889ec55ce3865f8c5,
title = "Angiopoietin-Tie Signaling Pathway in Endothelial Cells: A Computational Model",
abstract = "Biological",
keywords = "Bioinformatics, Biological Sciences, Cell Biology",
author = "Yu Zhang and Kontos, {Christopher D.} and Annex, {Brian H.} and Popel, {Aleksander S.}",
note = "Funding Information: The authors thank Dr. Adam Mirando for constructive comments. This work was supported by the National Institutes of Health grants R01HL101200 , R01CA138264 , and R01EY028996 (A.S.P.). Part of this research project was conducted using computational resources (and/or scientific computing services) at the Maryland Advanced Research Computing Center (MARCC). Funding Information: The authors thank Dr. Adam Mirando for constructive comments. This work was supported by the National Institutes of Health grants R01HL101200, R01CA138264, and R01EY028996 (A.S.P.). Part of this research project was conducted using computational resources (and/or scientific computing services) at the Maryland Advanced Research Computing Center (MARCC). Y.Z. and A.S.P. conceived and designed the study. C.D.K. and B.H.A. provided critical input into the study. Y.Z. implemented the model in BioNetGen, performed the computer simulations, analyzed the data, and drafted the manuscript. Y.Z. C.D.K. B.H.A. and A.S.P. participated in writing and editing the manuscript. C.D.K. serves on the Scientific Advisory Board for Aerpio Pharmaceuticals. The other authors declare no competing interests. Publisher Copyright: {\textcopyright} 2019 The Author(s)",
year = "2019",
month = oct,
day = "25",
doi = "10.1016/j.isci.2019.10.006",
language = "English (US)",
volume = "20",
pages = "497--511",
journal = "iScience",
issn = "2589-0042",
publisher = "Elsevier Inc.",
}