Abstract
In ventral prostate tissues of adult castrated rats, delta-9-tetrahydrocannabinol (THC) at 10 mg/kg for 7 days counteracted the testosterone-induced changes of DNA, RNA and protein content, the tartrate-insensitive form of acid phosphatase, and the isoenzyme variant of acid phosphatase associated with the secretory type enzyme. The results indicate that THC acts anti-androgenically and directly at the level of male accessory sex organs.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 513-517 |
| Number of pages | 5 |
| Journal | Journal of Reproduction and Fertility |
| Volume | 62 |
| Issue number | 2 |
| DOIs | |
| State | Published - 1981 |
ASJC Scopus subject areas
- Physiology
- Embryology
- Molecular Biology
- Obstetrics and Gynecology
- Developmental Biology
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