Application of hydrophobic resin adhesives to acid-etched dentin with an alternative wet bonding technique

Fernanda T. Sadek, David Henry Pashley, Yoshihiro Nishitani, Marcella R. Carrilho, Adam Donnelly, Marco Ferrari, Franklin Chi Meng Tay

Research output: Contribution to journalArticlepeer-review

89 Scopus citations


Hydrophilic dentin adhesives are prone to water sorption that adversely affects the durability of resin-dentin bonds. This study examined the feasibility of bonding to dentin with hydrophobic resins via the adaptation of electron microscopy tissue processing techniques. Hydrophobic primers were prepared by diluting 2,2-bis[4(2-hydroxy-3-methacryloyloxy-propyloxy)-phenyl] propane/triethyleneglycol dimethacrylate resins with known ethanol concentrations. They were applied to acid-etched moist dentin using an ethanol wet bonding technique that involved: (1) stepwise replacement of water with a series of increasing ethanol concentrations to prevent the demineralized collagen matrix from collapsing; (2) stepwise replacement of the ethanol with different concentrations of hydrophobic primers and subsequently with neat hydrophobic resin. Using the ethanol wet bonding technique, the experimental primer versions with 40, 50, and 75% resin exhibited tensile strengths which were not significantly different from commercially available hydrophilic three-step adhesives that were bonded with water wet bonding technique. The concept of ethanol wet bonding may be explained in terms of solubility parameter theory. This technique is sensitive to water contamination, as depicted by the lower tensile strength results from partial dehydration protocols. The technique has to be further improved by incorporating elements of dentin permeability reduction to avoid water from dentinal tubules contaminating water-free resin blends during bonding.

Original languageEnglish (US)
Pages (from-to)19-29
Number of pages11
JournalJournal of Biomedical Materials Research - Part A
Issue number1
StatePublished - Jan 1 2008


  • Acid-etch
  • Bis-GMA
  • Dentine
  • Ethanol
  • Hydrophobic resins
  • Stepwise
  • Wet bonding

ASJC Scopus subject areas

  • Ceramics and Composites
  • Biomaterials
  • Biomedical Engineering
  • Metals and Alloys


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