Applications of Chemical Ligation in Peptide Synthesis via Acyl Transfer

Siva S Panda

doi:10.1007/128_2014_608

Applications of Chemical Ligation in Peptide Synthesis via Acyl Transfer

Siva S Panda

Chemistry and Biochemistry

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

The utility of native chemical ligation (NCL) in the solution or solid phase synthesis of peptides, cyclic peptides, glycopeptides, and neoglycoconjugates is reviewed. In addition, the mechanistic details of inter- or intra-molecular NCLs are discussed from experimental and computational points of view.

Original language	English (US)
Pages (from-to)	229-65
Number of pages	37
Journal	Topics in Current Chemistry
Volume	362
DOIs	https://doi.org/10.1007/128_2014_608
State	Published - 2015

Keywords

Acylation
Molecular Structure
Peptides
Journal Article
Research Support, Non-U.S. Gov't
Review

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10.1007/128_2014_608

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title = "Applications of Chemical Ligation in Peptide Synthesis via Acyl Transfer",

abstract = "The utility of native chemical ligation (NCL) in the solution or solid phase synthesis of peptides, cyclic peptides, glycopeptides, and neoglycoconjugates is reviewed. In addition, the mechanistic details of inter- or intra-molecular NCLs are discussed from experimental and computational points of view.",

keywords = "Acylation, Molecular Structure, Peptides, Journal Article, Research Support, Non-U.S. Gov't, Review",

author = "Panda, {Siva S}",

year = "2015",

doi = "10.1007/128_2014_608",

language = "English (US)",

volume = "362",

pages = "229--65",

journal = "Topics in Current Chemistry",

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AU - Panda, Siva S

PY - 2015

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AB - The utility of native chemical ligation (NCL) in the solution or solid phase synthesis of peptides, cyclic peptides, glycopeptides, and neoglycoconjugates is reviewed. In addition, the mechanistic details of inter- or intra-molecular NCLs are discussed from experimental and computational points of view.

KW - Acylation

KW - Molecular Structure

KW - Peptides

KW - Journal Article

KW - Research Support, Non-U.S. Gov't

KW - Review

U2 - 10.1007/128_2014_608

DO - 10.1007/128_2014_608

M3 - Article

C2 - 25805142

SN - 0340-1022

VL - 362

SP - 229

EP - 265

JO - Topics in Current Chemistry

JF - Topics in Current Chemistry

ER -

Applications of Chemical Ligation in Peptide Synthesis via Acyl Transfer

Abstract

Keywords

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