The utility of native chemical ligation (NCL) in the solution or solid phase synthesis of peptides, cyclic peptides, glycopeptides, and neoglycoconjugates is reviewed. In addition, the mechanistic details of inter- or intra-molecular NCLs are discussed from experimental and computational points of view.
|Original language||English (US)|
|Number of pages||37|
|Journal||Topics in Current Chemistry|
|State||Published - 2015|
- Molecular Structure
- Journal Article
- Research Support, Non-U.S. Gov't