Arginine recycling in endothelial cells is regulated BY HSP90 and the ubiquitin proteasome system

Biochemistry, Genetics and Molecular Biology

• Proteasome 100%
• Ubiquitin 100%
• Argininosuccinate Lyase 100%
• Arginine 100%
• Argininosuccinate Synthase 88%
• Hsp90 66%
• C-Terminus 33%
• Nitric Oxide 33%
• Mutant Protein 22%
• Ubiquitin-Conjugating Enzyme 11%
• Geldanamycin 11%
• Heat Shock Protein 11%
• Hsp70 11%
• Urea Cycle 11%
• Nitric Oxide Synthase 11%
• Messenger RNA 11%
• Citrulline 11%

Keyphrases

• Endothelial Cells 100%
• Arginine 100%
• Heat Shock Protein 90 (Hsp90) 100%
• Ubiquitin-proteasome System 100%
• Argininosuccinate Lyase 100%
• Interacting Proteins 17%
• C-terminus 17%
• Hsc70 17%
• Overexpression 11%
• Recycling Pathway 11%
• Endothelial Nitric Oxide Synthase (eNOS) 5%
• Citrulline 5%
• Nitric Oxide 5%
• E3 Ubiquitin Ligase 5%
• Nitric Oxide Production 5%
• Heat Shock Proteins 5%
• Geldanamycin 5%
• Therapeutic Target 5%
• Proteasomal Degradation 5%
• Heat Shock Protein 70 (HSP70) 5%
• Nitric Oxide Signaling 5%
• Functional Complexity 5%
• Human Aortic Endothelial Cells 5%
• Molecular Regulation 5%
• Hsp90 Inhibitor 5%
• Protein Loss 5%
• Mutant Protein 5%
• Arginine Paradox 5%
• Protein mutants 5%
• U-box Domain 5%
• L-arginine-nitric Oxide 5%
• Urea Cycle Enzymes 5%
• Synthetic Enzyme Complex 5%
• Ubiquitin-proteasome Pathway 5%