Asenapine-induced restless legs syndrome: Differentiation from akathisia

W. Vaughn McCall, Mary Anne Riley, Chelsea Hodges, Laryssa McCloud, Marjorie Phillips, Peter B. Rosenquist

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Akathisia and restless legs syndrome (RLS) share some common clinical features and a common relationship with dopamine dysfunction. However, the underlying causes and appropriate treatments for akathisia and RLS are different. Herein we describe a case of RLS that was precipitated by a single dose of asenapine, which is an atypical antipsychotic, and dissect the features that support the contention that this was indeed a case of RLS and not akathisia.

Original languageEnglish (US)
Pages (from-to)1341-1342
Number of pages2
JournalJournal of Clinical Sleep Medicine
Issue number12
StatePublished - 2014


  • Akathisia
  • Asenapine
  • Restless leg syndrome

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Neurology
  • Clinical Neurology


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