Aspirin use among adults with cardiovascular disease in the United States: Implications for an intervention approach

Benjamin E. Ansa, Zachary Hoffman, Nicollette Lewis, Cassandra Savoy, Angela Hickson, Rebecca Stone, Tara Johnson

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


Cardiovascular disease (CVD) is a major underlying cause of death, with high economic burden in most countries, including the United States. Lifestyle modifications and the use of antiplatelet therapy, such as aspirin, can contribute significantly to secondary prevention of CVD in adults. This study examined the prevalence and associated factors of aspirin use for the secondary prevention of angina pectoris, myocardial infarction (MI), and cerebrovascular disease (stroke) in a sample of American adults. The 2015 Behavioral Risk Factor Surveillance System (BRFSS) dataset was analyzed for this cross-sectional study. Almost 16% of the study population (N = 441,456) had angina, MI, or stroke. Weighted percentages of respondents with angina, MI, and stroke were 4%, 4.3%, and 3%, respectively. Overall, weighted prevalence of daily (or every other day) aspirin use was about 65%, 71%, and 57% among respondents with angina, MI, and stroke, respectively. Factors that were significantly associated with aspirin use included male sex, more than high school education, high blood pressure, diabetes, and less than excellent general health. There were existing differences among individuals with CVD based on diagnosis, demographic and socioeconomic status in the use of aspirin for secondary prevention. Resources for promoting aspirin use should be directed toward groups with lower utilization.

Original languageEnglish (US)
Article number264
JournalJournal of Clinical Medicine
Issue number2
StatePublished - Feb 2019
Externally publishedYes


  • Angina
  • Aspirin
  • Cardiovascular disease
  • Myocardial infarction
  • Prevalence
  • Stroke
  • United states

ASJC Scopus subject areas

  • Medicine(all)


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