Behavioral determinants of 24-hour blood pressure patterns in borderline hypertension

Thomas G. Pickering, Gregory A. Harshfield, Seymour Blank, Gary D. James, John H. Laragh, Linda Clark, Lorraine Denby, Daryl Pregibon

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Borderline hypertension is a heterogeneous condition; only a minority of patients will progress to fixed essential hypertension or suffer cardiovascular damage. Ambulatory blood pressure monitoring can detect the subgroup of borderlines with sustained blood pressure elevation outside the office setting and can also provide a measure of blood pressure variability. Patients in the former group may be at greatest risk for cardiovascular complications while the latter have been theorized to be at risk for progression to fixed hypertension. Evidence we have gathered utilizing ambulatory monitoring does not support the contention that there is a subgroup of borderline hypertensives with excessive blood pressure variability in natural settings. Such recordings have been of benefit in identifying patients with excessive pressor responses to office visits. Future studies employing ambulatory monitoring may be useful in the detection of clinically important subgroups of borderline hypertension.

Original languageEnglish (US)
Pages (from-to)S89-S92
JournalJournal of Cardiovascular Pharmacology
StatePublished - 1986
Externally publishedYes


  • Ambulatory BP monitoring
  • BP reactivity
  • BP variability
  • Borderline hypertension

ASJC Scopus subject areas

  • Pharmacology
  • Cardiology and Cardiovascular Medicine


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