TY - JOUR
T1 - Beneficial role of phytochemicals on oxidative stress and age-related diseases
AU - Forni, Cinzia
AU - Facchiano, Francesco
AU - Bartoli, Manuela
AU - Pieretti, Stefano
AU - Facchiano, Antonio
AU - D'Arcangelo, Daniela
AU - Norelli, Sandro
AU - Valle, Giorgia
AU - Nisini, Roberto
AU - Beninati, Simone
AU - Tabolacci, Claudio
AU - Jadeja, Ravirajsinh N.
N1 - Funding Information:
The financial support from Italian Ministry of Health (Ricerca Corrente) is kindly acknowledged.
Publisher Copyright:
© 2019 Hindawi. All rights reserved.
PY - 2019
Y1 - 2019
N2 - Aging is related to a number of functional and morphological changes leading to progressive decline of the biological functions of an organism. Reactive Oxygen Species (ROS), released by several endogenous and exogenous processes, may cause important oxidative damage to DNA, proteins, and lipids, leading to important cellular dysfunctions. The imbalance between ROS production and antioxidant defenses brings to oxidative stress conditions and, related to accumulation of ROS, aging-associated diseases. The purpose of this review is to provide an overview of the most relevant data reported in literature on the natural compounds, mainly phytochemicals, with antioxidant activity and their potential protective effects on age-related diseases such as metabolic syndrome, diabetes, cardiovascular disease, cancer, neurodegenerative disease, and chronic inflammation, and possibly lower side effects, when compared to other drugs. & copy; 2019 Cinzia Forni et al.
AB - Aging is related to a number of functional and morphological changes leading to progressive decline of the biological functions of an organism. Reactive Oxygen Species (ROS), released by several endogenous and exogenous processes, may cause important oxidative damage to DNA, proteins, and lipids, leading to important cellular dysfunctions. The imbalance between ROS production and antioxidant defenses brings to oxidative stress conditions and, related to accumulation of ROS, aging-associated diseases. The purpose of this review is to provide an overview of the most relevant data reported in literature on the natural compounds, mainly phytochemicals, with antioxidant activity and their potential protective effects on age-related diseases such as metabolic syndrome, diabetes, cardiovascular disease, cancer, neurodegenerative disease, and chronic inflammation, and possibly lower side effects, when compared to other drugs. & copy; 2019 Cinzia Forni et al.
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U2 - 10.1155/2019/8748253
DO - 10.1155/2019/8748253
M3 - Review article
C2 - 31080832
AN - SCOPUS:85065639046
SN - 2314-6133
VL - 2019
JO - BioMed Research International
JF - BioMed Research International
M1 - 8748253
ER -
