BK virus and JC virus shed during pregnancy have predominantly archetypal regulatory regions

R. B. Markowitz; B. A. Eaton; M. F. Kubik; D. Latorra; J. A. McGregor; W. S. Dynan

doi:10.1128/jvi.65.8.4515-4519.1991

BK virus and JC virus shed during pregnancy have predominantly archetypal regulatory regions

R. B. Markowitz, B. A. Eaton, M. F. Kubik, D. Latorra, J. A. McGregor, W. S. Dynan

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127 Scopus citations

Abstract

Twenty-three BK virus and JC virus DNA samples obtained from urine of pregnant women had almost exclusively archetypal transcriptional control regions. Rearrangements characteristic of laboratory strains are apparently not required for reactivation in humans. Unexpectedly, alignment shows that many elements identified previously in the BK virus enhancer are conserved in the JC virus archetype.

Original language	English (US)
Pages (from-to)	4515-4519
Number of pages	5
Journal	Journal of Virology
Volume	65
Issue number	8
DOIs	https://doi.org/10.1128/jvi.65.8.4515-4519.1991
State	Published - 1991
Externally published	Yes

ASJC Scopus subject areas

Microbiology
Immunology
Insect Science
Virology

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10.1128/jvi.65.8.4515-4519.1991

Cite this

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abstract = "Twenty-three BK virus and JC virus DNA samples obtained from urine of pregnant women had almost exclusively archetypal transcriptional control regions. Rearrangements characteristic of laboratory strains are apparently not required for reactivation in humans. Unexpectedly, alignment shows that many elements identified previously in the BK virus enhancer are conserved in the JC virus archetype.",

author = "Markowitz, {R. B.} and Eaton, {B. A.} and Kubik, {M. F.} and D. Latorra and McGregor, {J. A.} and Dynan, {W. S.}",

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AU - Markowitz, R. B.

AU - Eaton, B. A.

AU - Kubik, M. F.

AU - Latorra, D.

AU - McGregor, J. A.

AU - Dynan, W. S.

PY - 1991

Y1 - 1991

N2 - Twenty-three BK virus and JC virus DNA samples obtained from urine of pregnant women had almost exclusively archetypal transcriptional control regions. Rearrangements characteristic of laboratory strains are apparently not required for reactivation in humans. Unexpectedly, alignment shows that many elements identified previously in the BK virus enhancer are conserved in the JC virus archetype.

AB - Twenty-three BK virus and JC virus DNA samples obtained from urine of pregnant women had almost exclusively archetypal transcriptional control regions. Rearrangements characteristic of laboratory strains are apparently not required for reactivation in humans. Unexpectedly, alignment shows that many elements identified previously in the BK virus enhancer are conserved in the JC virus archetype.

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BK virus and JC virus shed during pregnancy have predominantly archetypal regulatory regions

Abstract

ASJC Scopus subject areas

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