BK virus and JC virus shed during pregnancy have predominantly archetypal regulatory regions

Rhea Beth Markowitz; Benjamin A. Eaton; Mark F. Kubik; David Latorra; James A. McGregor; William S. Dynan

BK virus and JC virus shed during pregnancy have predominantly archetypal regulatory regions

Rhea Beth Markowitz, Benjamin A. Eaton, Mark F. Kubik, David Latorra, James A. McGregor, William S. Dynan

Research output: Contribution to journal › Article › peer-review

Abstract

Twenty-three BK virus and JC virus DNA samples obtained from urine of pregnant women had almost exclusively archetypal transcriptional control regions. Rearrangements characteristic of laboratory strains are apparently not required for reactivation in humans. Unexpectedly, alignment shows that many elements identified previously in the BK virus enhancer are conserved in the JC virus archetype.

Original language	English (US)
Pages (from-to)	4515-4519
Number of pages	5
Journal	Journal of Virology
Volume	65
Issue number	8
State	Published - Aug 1991
Externally published	Yes

ASJC Scopus subject areas

Microbiology
Immunology
Insect Science
Virology

Cite this

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title = "BK virus and JC virus shed during pregnancy have predominantly archetypal regulatory regions",

abstract = "Twenty-three BK virus and JC virus DNA samples obtained from urine of pregnant women had almost exclusively archetypal transcriptional control regions. Rearrangements characteristic of laboratory strains are apparently not required for reactivation in humans. Unexpectedly, alignment shows that many elements identified previously in the BK virus enhancer are conserved in the JC virus archetype.",

author = "Markowitz, {Rhea Beth} and Eaton, {Benjamin A.} and Kubik, {Mark F.} and David Latorra and McGregor, {James A.} and Dynan, {William S.}",

year = "1991",

month = aug,

language = "English (US)",

volume = "65",

pages = "4515--4519",

journal = "Journal of Virology",

issn = "0022-538X",

publisher = "American Society for Microbiology",

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T1 - BK virus and JC virus shed during pregnancy have predominantly archetypal regulatory regions

AU - Markowitz, Rhea Beth

AU - Eaton, Benjamin A.

AU - Kubik, Mark F.

AU - Latorra, David

AU - McGregor, James A.

AU - Dynan, William S.

PY - 1991/8

Y1 - 1991/8

N2 - Twenty-three BK virus and JC virus DNA samples obtained from urine of pregnant women had almost exclusively archetypal transcriptional control regions. Rearrangements characteristic of laboratory strains are apparently not required for reactivation in humans. Unexpectedly, alignment shows that many elements identified previously in the BK virus enhancer are conserved in the JC virus archetype.

AB - Twenty-three BK virus and JC virus DNA samples obtained from urine of pregnant women had almost exclusively archetypal transcriptional control regions. Rearrangements characteristic of laboratory strains are apparently not required for reactivation in humans. Unexpectedly, alignment shows that many elements identified previously in the BK virus enhancer are conserved in the JC virus archetype.

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M3 - Article

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AN - SCOPUS:0025913811

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BK virus and JC virus shed during pregnancy have predominantly archetypal regulatory regions

Abstract

ASJC Scopus subject areas

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