Bone marrow examination for metastatic tumor. Aspirate and biopsy

Gurmukh Singh, John R. Krause, Volker Breitfeld

Research output: Contribution to journalArticlepeer-review

60 Scopus citations


A 6‐year experience with bone marrow aspirates and biopsies (96 cases) positive for metastatic carcinoma is reviewed. Marrow examination detected secondary carcinoma in 58 cases (60%) despite negative roentgenographic and/or bone scan examinations. Breast carcinoma was the most frequent primary site. The bone marrow biopsy was superior to the aspirate in finding carcinoma (97% vs. 72%). However, in an occasional case, tumor was found only in aspirate preparations. Both procedures should be considered complementary and are recommended in the marrow evaluation of patients with carcinoma.

Original languageEnglish (US)
Pages (from-to)2317-2321
Number of pages5
Issue number5
StatePublished - Nov 1977
Externally publishedYes

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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