Bone metastasis from gynecologic carcinomas: A clinicopathologic study

Fadi W. Abdul-Karim, Masatoshi Kida, W. Budd Wentz, John R. Carter, Kelly Sorensen, Michael Macfee, Jocelyn Zika, John T. Makley

Research output: Contribution to journalArticlepeer-review

123 Scopus citations


Between 1948 and 1984, autopsies were performed on 305 patients with primary carcinomas of the cervix, endometrium, ovaries, fallopian tubes, vulva, and vagina. Skeletal metastases were detected premortem and at autopsy in 49 cases (16.1%): cervix, 20 (40.8%); endometrium, 17 (34.7%); ovary, 7 (14.3%); vulva, 4 (8.2%); fallopian tube, 1 (2%). There were no cases of osseous metastasis from vaginal carcinoma. The incidence and sites of metastasis from these gynecologic carcinomas were correlated with their clinical and histopathologic classifications. This clinicopathologic study, based on autopsy data, demonstrates that osseous metastases are not uncommon, are significantly greater than clinically appreciated, and correlate with advanced anatomic stage and histopathologic type and grade.

Original languageEnglish (US)
Pages (from-to)108-114
Number of pages7
JournalGynecologic Oncology
Issue number2
StatePublished - Nov 1990

ASJC Scopus subject areas

  • Oncology
  • Obstetrics and Gynecology


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