Bone Replacement Grafts for the Treatment of Periodontal Intrabony Defects

Philip J. Hanes

Research output: Contribution to journalReview articlepeer-review

27 Scopus citations


Bone replacement grafts, including autogenous grafts from intraoral donor sites, allografts, xenografts, and alloplastic bone substitutes, are the most widely used treatment modalities for the regeneration of periodontal osseous defects. Studies suggest a favorable clinical outcome with the use of these materials in terms of improvements in periodontal probing depths, probing attachment gains, and bone fill. In terms of bone fill, most studies report more than 50% resolution of intrabony defects when treated with bone replacement grafts. However, histologic evidence of periodontal regeneration, including new bone, periodontal ligament, and cementum, has been reported only for autogenous bone grafts and demineralized freeze-dried bone allografts.

Original languageEnglish (US)
Pages (from-to)499-512
Number of pages14
JournalOral and Maxillofacial Surgery Clinics of North America
Issue number4
StatePublished - Nov 2007

ASJC Scopus subject areas

  • Surgery
  • Oral Surgery
  • Otorhinolaryngology


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