Campylobacter jejuni CsrA mediates oxidative stress responses, biofilm formation, and host cell invasion

Joshua A. Fields; Stuart A. Thompson

doi:10.1128/JB.01928-07

Campylobacter jejuni CsrA mediates oxidative stress responses, biofilm formation, and host cell invasion

Joshua A. Fields, Stuart A. Thompson

Infectious Disease

Research output: Contribution to journal › Article › peer-review

115 Scopus citations

Abstract

The putative global posttranscriptional regulator csrA was mutated in Campylobacter jejuni 81-176. The csrA mutant was attenuated in surviving oxidative stress. CsrA also contributed to biofilm formation and adherence to and invasion of INT407 intestinal epithelial cells, suggesting a regulatory role for CsrA in C. jejuni pathogenesis.

Original language	English (US)
Pages (from-to)	3411-3416
Number of pages	6
Journal	Journal of Bacteriology
Volume	190
Issue number	9
DOIs	https://doi.org/10.1128/JB.01928-07
State	Published - May 2008

ASJC Scopus subject areas

Microbiology
Molecular Biology

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10.1128/JB.01928-07

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title = "Campylobacter jejuni CsrA mediates oxidative stress responses, biofilm formation, and host cell invasion",

abstract = "The putative global posttranscriptional regulator csrA was mutated in Campylobacter jejuni 81-176. The csrA mutant was attenuated in surviving oxidative stress. CsrA also contributed to biofilm formation and adherence to and invasion of INT407 intestinal epithelial cells, suggesting a regulatory role for CsrA in C. jejuni pathogenesis.",

author = "Fields, {Joshua A.} and Thompson, {Stuart A.}",

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AB - The putative global posttranscriptional regulator csrA was mutated in Campylobacter jejuni 81-176. The csrA mutant was attenuated in surviving oxidative stress. CsrA also contributed to biofilm formation and adherence to and invasion of INT407 intestinal epithelial cells, suggesting a regulatory role for CsrA in C. jejuni pathogenesis.

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JO - Journal of Bacteriology

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Campylobacter jejuni CsrA mediates oxidative stress responses, biofilm formation, and host cell invasion

Abstract

ASJC Scopus subject areas

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