Cardiovascular risk assessment and management of patients undergoing hematopoietic cell transplantation

Guilherme H. Oliveira; Sadeer G. Al-Kindi; Avirup Guha; Amit K. Dey; Isaac B. Rhea; Marcos J. deLima

doi:10.1038/s41409-020-01080-1

Cardiovascular risk assessment and management of patients undergoing hematopoietic cell transplantation

Guilherme H. Oliveira, Sadeer G. Al-Kindi, Avirup Guha, Amit K. Dey, Isaac B. Rhea, Marcos J. deLima

Cardiology

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

The purpose of this review is to provide a framework for the cardiovascular evaluation and management of patients undergoing hematopoietic cell transplantation (HCT). To accomplish this, we have performed an extensive literature review, critically analyzed the available evidence, and developed a set of recommendations to guide best practice. Herein, we discuss the cardiovascular risk profile of patients undergoing HCT along with putative mechanisms of HCT-induced cardiovascular injury. We then present an algorithm for cardiovascular testing and risk mitigation of potential recipients. Last, we address the management of the most prevalent cardiovascular conditions associated with HCT recipients.

Original language	English (US)
Pages (from-to)	544-551
Number of pages	8
Journal	Bone marrow transplantation
Volume	56
Issue number	3
DOIs	https://doi.org/10.1038/s41409-020-01080-1
State	Published - Mar 1 2021

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AU - Guha, Avirup

AU - Dey, Amit K.

AU - Rhea, Isaac B.

AU - deLima, Marcos J.

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AB - The purpose of this review is to provide a framework for the cardiovascular evaluation and management of patients undergoing hematopoietic cell transplantation (HCT). To accomplish this, we have performed an extensive literature review, critically analyzed the available evidence, and developed a set of recommendations to guide best practice. Herein, we discuss the cardiovascular risk profile of patients undergoing HCT along with putative mechanisms of HCT-induced cardiovascular injury. We then present an algorithm for cardiovascular testing and risk mitigation of potential recipients. Last, we address the management of the most prevalent cardiovascular conditions associated with HCT recipients.

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Cardiovascular risk assessment and management of patients undergoing hematopoietic cell transplantation

Abstract

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