Cell and tissue reaction of animal embryonic brain on hypoxia

V. A. Otellin; L. I. Khozhaj; E. G. Gilerovich; D. E. Korzhevskij; D. R. Gutsaeva; I. T. Demchenko; V. B. Kostkin; I. P. Grigor'ev

Cell and tissue reaction of animal embryonic brain on hypoxia

V. A. Otellin, L. I. Khozhaj, E. G. Gilerovich, D. E. Korzhevskij, D. R. Gutsaeva, I. T. Demchenko, V. B. Kostkin, I. P. Grigor'ev

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Abstract

Prenatal hypoxia and adaptive cell and tissue brain reaction have been investigated in rat embryos. Signs of apoptosis have been determined in brain tissue after 1 hour of hypoxidation of 13 day-old embryos. At the final stages of embryogenesis brain degeneration has decreased, but migration of neuroblasts was abnormal. At this period defense antihypoxial brain reactions have been formed. Induction of NOS activity in brain vessels stimulated oxygen transport in brain. This reaction was probably compensating in conditions of hypoxia.

Original language	English (US)
Pages (from-to)	703-705
Number of pages	3
Journal	Doklady Akademii Nauk
Volume	393
Issue number	5
State	Published - Dec 1 2003
Externally published	Yes

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title = "Cell and tissue reaction of animal embryonic brain on hypoxia",

abstract = "Prenatal hypoxia and adaptive cell and tissue brain reaction have been investigated in rat embryos. Signs of apoptosis have been determined in brain tissue after 1 hour of hypoxidation of 13 day-old embryos. At the final stages of embryogenesis brain degeneration has decreased, but migration of neuroblasts was abnormal. At this period defense antihypoxial brain reactions have been formed. Induction of NOS activity in brain vessels stimulated oxygen transport in brain. This reaction was probably compensating in conditions of hypoxia.",

author = "Otellin, {V. A.} and Khozhaj, {L. I.} and Gilerovich, {E. G.} and Korzhevskij, {D. E.} and Gutsaeva, {D. R.} and Demchenko, {I. T.} and Kostkin, {V. B.} and Grigor'ev, {I. P.}",

year = "2003",

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language = "English (US)",

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T1 - Cell and tissue reaction of animal embryonic brain on hypoxia

AU - Otellin, V. A.

AU - Khozhaj, L. I.

AU - Gilerovich, E. G.

AU - Korzhevskij, D. E.

AU - Gutsaeva, D. R.

AU - Demchenko, I. T.

AU - Kostkin, V. B.

AU - Grigor'ev, I. P.

PY - 2003/12/1

Y1 - 2003/12/1

N2 - Prenatal hypoxia and adaptive cell and tissue brain reaction have been investigated in rat embryos. Signs of apoptosis have been determined in brain tissue after 1 hour of hypoxidation of 13 day-old embryos. At the final stages of embryogenesis brain degeneration has decreased, but migration of neuroblasts was abnormal. At this period defense antihypoxial brain reactions have been formed. Induction of NOS activity in brain vessels stimulated oxygen transport in brain. This reaction was probably compensating in conditions of hypoxia.

AB - Prenatal hypoxia and adaptive cell and tissue brain reaction have been investigated in rat embryos. Signs of apoptosis have been determined in brain tissue after 1 hour of hypoxidation of 13 day-old embryos. At the final stages of embryogenesis brain degeneration has decreased, but migration of neuroblasts was abnormal. At this period defense antihypoxial brain reactions have been formed. Induction of NOS activity in brain vessels stimulated oxygen transport in brain. This reaction was probably compensating in conditions of hypoxia.

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M3 - Article

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JO - Doklady Akademii Nauk

JF - Doklady Akademii Nauk

IS - 5

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Cell and tissue reaction of animal embryonic brain on hypoxia

Abstract

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