Abstract
Diabetes not only increases the risk but also worsens the motor and cognitive recovery after stroke, which is the leading cause of disability worldwide. Repair after stroke requires coordinated communication among various cell types in the central nervous system as well as circulating cells. Vascular restoration is critical for the enhancement of neurogenesis and neuroplasticity. Given that vascular disease is a major component of all complications associated with diabetes including stroke, this review will focus on cellular communications that are important for vascular restoration in the context of diabetes. This article is part of a Special Issue entitled SI: Cell Interactions In Stroke.
Original language | English (US) |
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Pages (from-to) | 81-96 |
Number of pages | 16 |
Journal | Brain Research |
Volume | 1623 |
DOIs | |
State | Published - Oct 14 2015 |
Keywords
- Angiogenesis
- Diabetes
- Stroke
- Vascular restoration
ASJC Scopus subject areas
- General Neuroscience
- Molecular Biology
- Clinical Neurology
- Developmental Biology