Chronic spinal cord transection does not affect peripheral nerve regeneration

Adarsh K. Gulati, Thomas R. Swift, Russell L. McBride, Earl R. Feringa

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Spinal cord transection is known to cause progressive changes in motor neurons and hind limb muscles. In the present study, regeneration of the peroneal nerve was examined in rats 25 weeks after a T9 spinal cord transection. Successful regeneration and innervation of the target muscle was observed after crush injury to the nerve in the spinal cord transected animals. It is concluded that the ability of peripheral nerve to regenerate remains preserved after spinal cord injury.

Original languageEnglish (US)
Pages (from-to)361-364
Number of pages4
JournalRestorative Neurology and Neuroscience
Volume1
Issue number5
DOIs
StatePublished - Jan 1 1990

Keywords

  • Motor neuron
  • Peripheral nerve
  • Rat
  • Regeneration
  • Spinal cord
  • Transection

ASJC Scopus subject areas

  • Neurology
  • Developmental Neuroscience
  • Clinical Neurology

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