Computed tomographic screening for lung cancer: Individualising the benefit of the screening

C. I. Henschke; D. F. Yankelevitz; D. I. McCauley; S. Sone; T. Hanaoka; S. Markowitz; A. Miller; K. Klingler; T. Scherer; R. Inderbitzi; J. Zulueta; L. Montuenga; G. Bastarrika; S. Giunta; M. Crecco; P. Pugliese; M. Tockman; D. Shaham; K. Rice; R. Aye; H. Roberts; D. Patsios; T. Bauer; J. Lally; J. H.M. Austin; G. D.N. Pearson; D. Naidich; G. McGuinness; M. Rifkin; E. Fiore; S. Kopel; D. Klippenstein; A. Litwin; P. A. Loud; L. J. Kohman; E. M. Scalzetti; A. Khan; R. Shah; M. V. Smith; H. T. Williams; L. Lovett; D. S. Mendelson; R. Thurer; R. T. Heelan; M. S. Ginsberg; F. Sullivan; M. Ottinger; D. Vafai; T. A.S. Matalon; S. L. Odzer; X. Liu; B. Sheppard; E. Cole; P. H. Wiernik; D. Ray; H. Pass; C. Endress; D. Mullen; M. Kalafer; F. Grannis; A. Rotter; M. K. Thorsen; R. Hansen; E. Camacho; D. Luedke

doi:10.1183/09031936.00000607

Computed tomographic screening for lung cancer: Individualising the benefit of the screening

C. I. Henschke, D. F. Yankelevitz, D. I. McCauley, S. Sone, T. Hanaoka, S. Markowitz, A. Miller, K. Klingler, T. Scherer, R. Inderbitzi, J. Zulueta, L. Montuenga, G. Bastarrika, S. Giunta, M. Crecco, P. Pugliese, M. Tockman, D. Shaham, K. Rice, R. AyeH. Roberts, D. Patsios, T. Bauer, J. Lally, J. H.M. Austin, G. D.N. Pearson, D. Naidich, G. McGuinness, M. Rifkin, E. Fiore, S. Kopel, D. Klippenstein, A. Litwin, P. A. Loud, L. J. Kohman, E. M. Scalzetti, A. Khan, R. Shah, M. V. Smith, H. T. Williams, L. Lovett, D. S. Mendelson, R. Thurer, R. T. Heelan, M. S. Ginsberg, F. Sullivan, M. Ottinger, D. Vafai, T. A.S. Matalon, S. L. Odzer, X. Liu, B. Sheppard, E. Cole, P. H. Wiernik, D. Ray, H. Pass, C. Endress, D. Mullen, M. Kalafer, F. Grannis, A. Rotter, M. K. Thorsen, R. Hansen, E. Camacho, D. Luedke

Radiology and Imaging

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Individuals concerned about their risk of lung cancer are recommended to talk with their physicians about computed tomographic screening for lung cancer. To provide the necessary information, the survival benefit of the screening, specific to a particular person for a particular round of screening, is needed. The probability of survival gain from the first, baseline, round of screening was addressed as the product of: 1) the screening resulting in a diagnosis of lung cancer; 2) not dying from some other cause for a sufficiently long period of time; and 3) cure resulting from pre-symptomatic treatment of lung cancer. These probabilities were estimated using the International Early Lung Cancer Action Program data on individuals aged 40-85 yrs with a cigarette smoking history of 0-150 pack-yrs. The estimated probability of survival gain ranged from 0.4% for a 60-yr-old with a 10-pack-yr smoking history who quit smoking 20 yrs ago, to 3.1% for a 70-yr-old current smoker with a 100 pack-yr history and 2.0% for an 85-yr-old current smoker with a 150-pack-yr history. When seeking counsel about initiation of screening for lung cancer, an estimate of the probability of survival gain from the first round of computed tomographic screening, specific to the person's age and history of smoking, can be provided. Copyright

Original language	English (US)
Pages (from-to)	843-847
Number of pages	5
Journal	European Respiratory Journal
Volume	30
Issue number	5
DOIs	https://doi.org/10.1183/09031936.00000607
State	Published - Nov 2007

Keywords

International Early Lung Cancer Action Program
Lung cancer
Survival

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1183/09031936.00000607

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Henschke, C. I., Yankelevitz, D. F., McCauley, D. I., Sone, S., Hanaoka, T., Markowitz, S., Miller, A., Klingler, K., Scherer, T., Inderbitzi, R., Zulueta, J., Montuenga, L., Bastarrika, G., Giunta, S., Crecco, M., Pugliese, P., Tockman, M., Shaham, D., Rice, K., ... Luedke, D. (2007). Computed tomographic screening for lung cancer: Individualising the benefit of the screening. European Respiratory Journal, 30(5), 843-847. https://doi.org/10.1183/09031936.00000607

Henschke, CI, Yankelevitz, DF, McCauley, DI, Sone, S, Hanaoka, T, Markowitz, S, Miller, A, Klingler, K, Scherer, T, Inderbitzi, R, Zulueta, J, Montuenga, L, Bastarrika, G, Giunta, S, Crecco, M, Pugliese, P, Tockman, M, Shaham, D, Rice, K, Aye, R, Roberts, H, Patsios, D, Bauer, T, Lally, J, Austin, JHM, Pearson, GDN, Naidich, D, McGuinness, G, Rifkin, M, Fiore, E, Kopel, S, Klippenstein, D, Litwin, A, Loud, PA, Kohman, LJ, Scalzetti, EM, Khan, A, Shah, R, Smith, MV, Williams, HT, Lovett, L, Mendelson, DS, Thurer, R, Heelan, RT, Ginsberg, MS, Sullivan, F, Ottinger, M, Vafai, D, Matalon, TAS, Odzer, SL, Liu, X, Sheppard, B, Cole, E, Wiernik, PH, Ray, D, Pass, H, Endress, C, Mullen, D, Kalafer, M, Grannis, F, Rotter, A, Thorsen, MK, Hansen, R, Camacho, E & Luedke, D 2007, 'Computed tomographic screening for lung cancer: Individualising the benefit of the screening', European Respiratory Journal, vol. 30, no. 5, pp. 843-847. https://doi.org/10.1183/09031936.00000607

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title = "Computed tomographic screening for lung cancer: Individualising the benefit of the screening",

abstract = "Individuals concerned about their risk of lung cancer are recommended to talk with their physicians about computed tomographic screening for lung cancer. To provide the necessary information, the survival benefit of the screening, specific to a particular person for a particular round of screening, is needed. The probability of survival gain from the first, baseline, round of screening was addressed as the product of: 1) the screening resulting in a diagnosis of lung cancer; 2) not dying from some other cause for a sufficiently long period of time; and 3) cure resulting from pre-symptomatic treatment of lung cancer. These probabilities were estimated using the International Early Lung Cancer Action Program data on individuals aged 40-85 yrs with a cigarette smoking history of 0-150 pack-yrs. The estimated probability of survival gain ranged from 0.4% for a 60-yr-old with a 10-pack-yr smoking history who quit smoking 20 yrs ago, to 3.1% for a 70-yr-old current smoker with a 100 pack-yr history and 2.0% for an 85-yr-old current smoker with a 150-pack-yr history. When seeking counsel about initiation of screening for lung cancer, an estimate of the probability of survival gain from the first round of computed tomographic screening, specific to the person's age and history of smoking, can be provided. Copyright",

keywords = "International Early Lung Cancer Action Program, Lung cancer, Survival",

author = "Henschke, {C. I.} and Yankelevitz, {D. F.} and McCauley, {D. I.} and S. Sone and T. Hanaoka and S. Markowitz and A. Miller and K. Klingler and T. Scherer and R. Inderbitzi and J. Zulueta and L. Montuenga and G. Bastarrika and S. Giunta and M. Crecco and P. Pugliese and M. Tockman and D. Shaham and K. Rice and R. Aye and H. Roberts and D. Patsios and T. Bauer and J. Lally and Austin, {J. H.M.} and Pearson, {G. D.N.} and D. Naidich and G. McGuinness and M. Rifkin and E. Fiore and S. Kopel and D. Klippenstein and A. Litwin and Loud, {P. A.} and Kohman, {L. J.} and Scalzetti, {E. M.} and A. Khan and R. Shah and Smith, {M. V.} and Williams, {H. T.} and L. Lovett and Mendelson, {D. S.} and R. Thurer and Heelan, {R. T.} and Ginsberg, {M. S.} and F. Sullivan and M. Ottinger and D. Vafai and Matalon, {T. A.S.} and Odzer, {S. L.} and X. Liu and B. Sheppard and E. Cole and Wiernik, {P. H.} and D. Ray and H. Pass and C. Endress and D. Mullen and M. Kalafer and F. Grannis and A. Rotter and Thorsen, {M. K.} and R. Hansen and E. Camacho and D. Luedke",

year = "2007",

month = nov,

doi = "10.1183/09031936.00000607",

language = "English (US)",

volume = "30",

pages = "843--847",

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T1 - Computed tomographic screening for lung cancer

T2 - Individualising the benefit of the screening

AU - Henschke, C. I.

AU - Yankelevitz, D. F.

AU - McCauley, D. I.

AU - Sone, S.

AU - Hanaoka, T.

AU - Markowitz, S.

AU - Miller, A.

AU - Klingler, K.

AU - Scherer, T.

AU - Inderbitzi, R.

AU - Zulueta, J.

AU - Montuenga, L.

AU - Bastarrika, G.

AU - Giunta, S.

AU - Crecco, M.

AU - Pugliese, P.

AU - Tockman, M.

AU - Shaham, D.

AU - Rice, K.

AU - Aye, R.

AU - Roberts, H.

AU - Patsios, D.

AU - Bauer, T.

AU - Lally, J.

AU - Austin, J. H.M.

AU - Pearson, G. D.N.

AU - Naidich, D.

AU - McGuinness, G.

AU - Rifkin, M.

AU - Fiore, E.

AU - Kopel, S.

AU - Klippenstein, D.

AU - Litwin, A.

AU - Loud, P. A.

AU - Kohman, L. J.

AU - Scalzetti, E. M.

AU - Khan, A.

AU - Shah, R.

AU - Smith, M. V.

AU - Williams, H. T.

AU - Lovett, L.

AU - Mendelson, D. S.

AU - Thurer, R.

AU - Heelan, R. T.

AU - Ginsberg, M. S.

AU - Sullivan, F.

AU - Ottinger, M.

AU - Vafai, D.

AU - Matalon, T. A.S.

AU - Odzer, S. L.

AU - Liu, X.

AU - Sheppard, B.

AU - Cole, E.

AU - Wiernik, P. H.

AU - Ray, D.

AU - Pass, H.

AU - Endress, C.

AU - Mullen, D.

AU - Kalafer, M.

AU - Grannis, F.

AU - Rotter, A.

AU - Thorsen, M. K.

AU - Hansen, R.

AU - Camacho, E.

AU - Luedke, D.

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N2 - Individuals concerned about their risk of lung cancer are recommended to talk with their physicians about computed tomographic screening for lung cancer. To provide the necessary information, the survival benefit of the screening, specific to a particular person for a particular round of screening, is needed. The probability of survival gain from the first, baseline, round of screening was addressed as the product of: 1) the screening resulting in a diagnosis of lung cancer; 2) not dying from some other cause for a sufficiently long period of time; and 3) cure resulting from pre-symptomatic treatment of lung cancer. These probabilities were estimated using the International Early Lung Cancer Action Program data on individuals aged 40-85 yrs with a cigarette smoking history of 0-150 pack-yrs. The estimated probability of survival gain ranged from 0.4% for a 60-yr-old with a 10-pack-yr smoking history who quit smoking 20 yrs ago, to 3.1% for a 70-yr-old current smoker with a 100 pack-yr history and 2.0% for an 85-yr-old current smoker with a 150-pack-yr history. When seeking counsel about initiation of screening for lung cancer, an estimate of the probability of survival gain from the first round of computed tomographic screening, specific to the person's age and history of smoking, can be provided. Copyright

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KW - International Early Lung Cancer Action Program

KW - Lung cancer

KW - Survival

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Computed tomographic screening for lung cancer: Individualising the benefit of the screening

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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